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Journal of Clinical Neurology (Korea 2009-Mar

Intravenous recombinant tissue plasminogen activator thrombolysis in a patient with acute ischemic stroke secondary to aortic dissection.

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Keun-Sik Hong
So-Young Park
Seon-Il Whang
So-Young Seo
Dong-Ha Lee
Han-Joon Kim
Joong-Yang Cho
Yong-Jin Cho
Woo-Ik Jang
Chang Young Kim

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Resumo

BACKGROUND

Acute ischemic stroke secondary to aortic dissection (AoD) is challenging in the era of thrombolysis owing to the diagnostic difficulty within a narrow time window and the high risk of complications.

METHODS

A 64-year-old woman with middle cerebral artery occlusion syndrome admitted to the emergency room within intravenous recombinant tissue plasminogen activator (rt-PA) time window. Her neurological symptoms improved during thrombolysis, but chest and abdominal pain developed. Repeated history-taking, physical examination, and imaging studies led to the timely diagnosis and surgical treatment of AoD, which produced a successful outcome.

CONCLUSIONS

Clinical suspicion is invaluable for the diagnosis of this rare cause of stroke. Considering the stroke mechanism and complications, the risks of thrombolysis might outweigh its benefits.

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