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Journal de gynecologie, obstetrique et biologie de la reproduction 1977-Jan

[Unsaponifiable fractions of the avocado and soy bean in gyneocology].

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R Trevoux

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The experimental work of Robert on the action of the unsaponifiable fractions of the avocado pear and soya bean on inflammatory granulomata of the rat gives rise to the supposition that these have a selective action on inflamed connective tissue by a process of katabolism of collagen through proteolytic enzymes. We have used this anti-inflammatory and collagenolytic action in gynaecology, with favourable results particularly in post-inflammatory and post-infective conditions as well as scarring in the pelvis. The decongesting action of the unsaponifiables of the avocado pear and the soya bean seems also to have a role to play in cellular tissue reactions in the pelvis after cobalt therapy, and in recent retractile scars and in breast inflammations, as well as to prevent scar reactions after operations. Since treatment has to be for a long time and well tolerated, the blood lipids should be estimated as a safety measure. If this is done the unsaponifiables seem to have a place in the treatment of inflammatory conditions in gynaecology.

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