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aberrant crypt foci/panax
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Inhibition by ginseng of 1,2-dimethylhydrazine induction of aberrant crypt foci in the rat colon.
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The modifying effects of dietary administration of ginseng on the induction and development of 1,2-dimethylhydrazine (DMH)-induced aberrant crypt foci (ACF) were investigated in Fischer 344 (F-344) rats. In Experiment 1, starting at six weeks of age, 65 rats were injected with DMH or saline alone
Modulation of aberrant crypt foci and apoptosis by dietary herbal supplements (quercetin, curcumin, silymarin, ginseng and rutin).
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It is estimated that one-third of Americans use dietary herbal supplements on a regular basis. Diets rich in bioactive phytochemicals are associated with reduced risk of certain cancers, notably, colon cancer. Herbal supplements have not been directly tested as sources of bioactive cancer
White, but not Red, Ginseng Inhibits Progression of Intestinal Carcinogenesis in Rats.
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Ginseng is a well known traditional medicine in Asian countries which has attracted attention as a potential chemopreventive agent. In the present study, inhibitory effects of white and red ginseng on tumor development were examined using medium-term liver and multi-organ carcinogenicity bioassay
Colon cancer chemoprevention with ginseng and other botanicals.
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Colorectal cancer is becoming increasingly common in Asian countries and still remains the second leading cause of cancer deaths in the United States. Efforts to prevent colon cancer have targeted early detection through screening and chemoprevention. For the last ten years our laboratory has
Inhibition by ginseng of colon carcinogenesis in rats.
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The inhibitory effects of ginseng on the development of 1,2-dimethylhydrazine (DMH)-induced aberrant crypt foci (ACF) in the colon were investigated in rats. Male, 6-week-old rats were injected with DMH once a week for 4 weeks. Rats in Groups 1 and 2 were fed diets containing red and white ginseng,
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