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Página 1 a partir de 34 resultados
Effect of RIC on 2,3-BPG in Erythrocyte (RIC-BPG)
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RIC is induced by short-term insulting blood-flow of nonvital distant organs intermittently and has been proved to be effective in ischemic stroke and myocardial infarction(MI).The possible mechanisms of RIC protection is complicated.RIC leads to local ischemia and hypoxia and has been demonstrated
Control of Renal Oxygen Consumption, Mitochondrial Dysfunction, and Insulin Resistance
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Alternative Substrates in the Critically Ill Subject
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Aggressive muscle wasting occurs early in critical illness, and is associated with a greater number of days on a ventilator, increased length of intensive care unit (ICU) and/or hospital stay, and subsequent functional impairment which may last years. Hospital care costs, and ongoing costs of
Assessment of Disease Severity, Progression and Treatment in Infected Patients Presenting to the Emergency Department
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Despite significant improvements in diagnostic and preventative measures, the incidence of sepsis has continued to escalate rapidly in hospitalized patients, with mortality rates ranging between 10 - 54%, depending on the level of severity. The earliest possible identification and assessment of
Preventing Acute Kidney Injury (AKI) in Neonates
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Cardiac palliative/ correction surgeries in the newborns, infants, and children involve significant morbidity and mortality risks. Kidney function is frequently affected from cardiothoracic surgery in these children. Studies identify the incidence of acute kidney injury (AKI) to be approximately 54%
Morphine or/and Ketamine in Out-of-hospital Cardiac Arrest
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Almost 35 years ago, Dr Peter Safar wrote that "cerebral recovery from more than 5 min of cardiac arrest is hampered by complex secondary derangements of multiple organ systems after reperfusion". Actually, these 5 "golden" minutes determine the ability of cerebral neurones to regain ordinary
Pyridoxine, P2 Receptor Antagonism, and ATP-mediated Vasodilation in Young Adults
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Adenosine triphosphate (ATP) is an established vasodilator that is released from red blood cells during a variety of stimuli including exercise and exposure to hypoxic environments. Many studies have shown that infusion of ATP can lead to vasodilation similar to that which is achieved during
Mild Intermittent Hypoxia and Its Multipronged Effect on Sleep Apnea
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The dogma over the past 3 decades, particularly in the field of sleep medicine, has been that intermittent hypoxia (IH) is a detrimental stimulus that leads to a number of co‐morbidities including autonomic (e.g. increased sympathetic nervous system activity), cardiovascular (e.g. hypertension,
Itraconazole in Non Small Cell Lung Cancer
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Lung cancer is the leading cause of cancer death in the United States
The American Cancer Society estimates lung cancer incidence in the United States for 2018 to be about 234,030 and about 154,050 deaths.
In 2012, GLOBOCAN estimated that 1.8 million people were diagnosed with lung cancer,
Intermittent Hypoxia and Caffeine in Infants Born Preterm
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Acute morbidities can contribute to adverse neurodevelopment outcomes in preterm infants born at ≤30 wks gestation, but neural damage occurring after resolution of acute morbidities may be more subtle and related to cycles of inflammation and repair in the developing brain. One possible contributor
The Effect of A2A Adrenoceptor Stimulation on the Diameter of Retinal Arterioles During Hypoxia in Vivo
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Background:
Occlusion of the retinal vessels leading to retinal ischaemia and hypoxia is an important element in the pathophysiology of the major vision threatening diseases in the Western World. The hypoxic areas release vasodilating factors that induce vasodilatation in adjacent retinal areas in
GapCO2 and Respiratory Rate in Patients Under Volume Mechanical Ventilation
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An increased ∆PCO2 (> 6 mmHg) could be used to identify patients who still remain inadequately resuscitated, when deciding when to continue resuscitation despite a central venous oxygen saturation (ScvO2) > 70% associated with elevated blood lactate levels.
Under steady states of both VO2 and VCO2,
Oxidative Stress and Apoptosis of Energy Metabolism by Deferiprone From the Circulating Lymphocytes
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The study collection of PBMC and platelets from 30 patient having Parkinson's disease 30 patients having Amyotrophic lateral sclerosis and 30 healthy controls.
The collection will be performed either by cytapheresis for half of the patient and by collecting the whole blood for the other half.
PBMC
Long-term Remote Ischemic Preconditioning Improve Long-term Prognosis of Acute Myocardial Infarction Patients Without Emergency Reperfusion Therapy
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Long-term Remote Ischemic Preconditioning Improve the Prognosis of Myocardial Infarction Patients With Emergency Reperfusion Therapy
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