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adenosine/hypoxia

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10 resultados

Allosteric adenosine receptor modulators

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BACKGROUND OF THE INVENTION The present invention relates to certain thiophene derivatives and their use in the practice of medicine as allosteric modulators of adenosine receptors. Adenosine (Ado) is an autocoid (or local hormone) that modulates numerous functions in the cardiovascular and other

Allosteric adenosine receptor modulators

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Entrar Inscrever-se
BACKGROUND OF THE INVENTION The present invention relates to certain thiophene derivatives and their use in the practice of medicine as allosteric modulators of adenosine receptors. Adenosine (Ado) is an autocoid (or local hormone) that modulates numerous functions in the cardiovascular and other

Allosteric adenosine receptor modulators

Apenas usuários registrados podem traduzir artigos
Entrar Inscrever-se
FIELD OF THE INVENTION The present invention relates to certain thiophene derivatives and their use in the practice of medicine as allosteric modulators of adenosine receptors. BACKGROUND OF THE INVENTION Adenosine (Ado) is an autocoid (or local hormone) that modulates numerous functions in the

Allosteric adenosine receptor modulators

Apenas usuários registrados podem traduzir artigos
Entrar Inscrever-se
BACKGROUND OF THE INVENTION FIELD OF THE INVENTION The present invention relates to certain thiophene derivatives and their use in the practice of medicine as allosteric modulators of adenosine receptors. Adenosine (Ado) is an autocoid (or local hormone) that modulates numerous functions in the

Allosteric adenosine receptor modulators

Apenas usuários registrados podem traduzir artigos
Entrar Inscrever-se
FIELD OF THE INVENTION The present invention relates to certain thiophene derivatives and their use in the practice of medicine as allosteric modulators of adenosine receptors. BACKGROUND OF THE INVENTION Adenosine (Ado) is an autocoid (or local hormone) that modulates numerous functions in the

Thiophenes useful for modulating the adenosine receptor

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Entrar Inscrever-se
FIELD OF THE INVENTION The present invention relates to certain thiophene derivatives and their use in the practice of medicine as allosteric modulators of adenosine receptors. BACKGROUND OF THE INVENTION Adenosine (Ado) is an autocoid (or local hormone) that modulates numerous functions in the

Sulfo-derivatives of adenosine

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TECHNICAL FIELD OF THE INVENTION The present invention relates to improvements in medical therapy of certain traumas wherein bodily tissues are oxygen-deprived and, more particularly, to certain sulfo-derivatives of adenosine, their syntheses, and their pharmaceutical formulations. BACKGROUND OF THE

Use of adenosine uptake inhibitors for treating retinal or optic nerve head damage

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The present invention relates to the field of ophthalmology. In particular, the present invention relates to the treatment of retinal tissues. More specifically, the present invention discloses compositions and methods of using adenosine uptake inhibitors in the prevention or treatment of retinal

Adenosine receptor ligands and their use in the treatment of disease

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FIELD OF THE INVENTION The present invention is generally related to compounds useful as adenosine receptor ligand and more particularly to compounds showing activity as modulators of the andenosine receptor system. BACKGROUND OF THE INVENTION Several compounds related to general formula I have been

Pyridone substituted benzothiazole derivatives

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BACKGROUND OF THE INVENTION The present invention generally relates to pyridone substituted benzothiazole compounds that are adenosine receptor ligands. Specifically, the compounds of the present invention have a good affinity to the A.sub.2A -receptor and a high selectivity to the A.sub.1 - and
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