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adenosine/necrose

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6 resultados

Method of effecting immunosuppression by administering carbocyclic adenosine analogs

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FIELD OF THE INVENTION This invention relates to certain carbocyclic adenosine analogs which are useful as immunosuppressants. BACKGROUND OF THE INVENTION Immunity is concerned with the recognition and disposal of foreign antigenic material which is present in the body. Typically the antigens are in

Pharmaceutical therapy for congestive heart failure

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BACKGROUND OF THE INVENTION Nearly four million patients in the U.S. carry the diagnosis of congestive heart failure and congestive heart failure represents the most common discharge diagnosis (DRG) at hospitals across the U.S. In 1995, the Healthcare Finance Commission spent over 15 billion dollars

Pharmaceutical compositions and method of using same for the treatment of failing myocardial tissue

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BACKGROUND OF THE INVENTION Nearly four million patients in the U.S. carry the diagnosis of congestive heart failure and congestive heart failure represents the most common discharge diagnosis (DRG) at hospitals across the U.S. In 1995, the Healthcare Finance Commission spent over 15 billion dollars

Solution for the preservation of hearts

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BACKGROUND OF THE INVENTION (1) Field of the Invention The present invention relates to solutions for the preservation of hearts. More particularly, this invention relates to preservation solutions for perfusing and storing a heart while awaiting transplantation, and to methods for using the

PARP inhibitors

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FIELD OF THE INVENTION The present invention relates to new inhibitors of the nucleic enzyme poly(adenosine 5'-diphospho-ribose) polymerase ["poly(ADP-ribose) polymerase" or "PARP", which is also sometimes called "PARS" for poly(ADP-ribose) synthetase]. More particularly, the invention relates to

Methods and apparatus for treatment of chronic kidney disease

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FIELD The invention relates to treatment of kidney disease. More particularly, the invention relates to methods and apparatus for treating chronic kidney disease utilizing pulsed electromagnetic fields. BACKGROUND Kidneys are bean-shaped organs that serve as a biological filter removing metabolic
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