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anthraquinone/cancro
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Página 1 a partir de 40 resultados
Anthraquinone compounds as anti cancer compounds
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The present invention relates to a series of substituted alkylaminoanthraquinones, with nitrogen containing heterocyclic substituents, as well as N-oxides of these compounds. The compounds may be alkylating agents having topoisomerase II inhibiting activities. The N-oxides are prodrugs.
Resistance
Method for inhibiting growth of cancer cells and cell telomere and diseases of cell proliferation by using heteroannelated anthraquinone derivative compounds
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FIELD OF THE INVENTION
The present invention relates to heteroannelated anthraquinone derivatives for inhibiting a proliferation activity of a cancer cell, and more particularly to a series of heteroannelated anthraquinone derivatives and the synthesis method thereof.
BACKGROUND OF THE INVENTION
In
Heteroannelated anthraquinone derivatives for inhibiting cancers
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FIELD OF THE INVENTION
The present invention relates to heteroannelated anthraquinone derivatives and their use in treating cancers, and in particular their use in methods for inducing apoptosis, inhibiting telomerase activity and inhibiting abnormal cellular proliferation in living cells, tissues
Anti-neoplastic 1,4-bis-(substituted aminoalkyl amino)-anthraquinones
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BACKGROUND OF THE INVENTION
This invention relates to 1,4-bis-(substituted aminoalkylamino)-anthraquinones, and more particularly to the same as anti-neoplastic agents against animal neoplasms. 1,4-bis-substituted anthraquinones have long been known in the prior art as dyes. For example, U.S. Pat.
Lipsome/anthraquinone drug composition and method
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FIELD OF THE INVENTION
The present invention relates to an improved liposome/anthraquinone therapeutic composition having reduced lipid oxidation and free-radical damage, and to methods for preparing and using the composition.
REFERENCES
Aubel-Sadron, G., et al, Biochemie, 66: 333 (1984).
Augustin,
Liposome/anthraquinone drug composition and method
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1. FIELD OF THE INVENTION
The present invention relates to an improved liposome/anthraquinone therapeutic composition having reduced lipid oxidation and free-radical damage, and to methods for preparing and using the composition.
2. REFERENCES
Aubel-Sadron, G., et al, Biochemie, 66:333
Metal chelates of 1,4-bis(substituted-amino-5,8-dihydroxy-anthraquinones
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SUMMARY OF THE INVENTION
This invention relates to metal chelates of new organic compounds and, more particularly, is concerned with metal chelates of symmetrical 1,4-bis(substituted-amino)-5,8-dihydroxyanthraquinones which are represented by the following general formula: ##STR1## wherein Q is a
1, 2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to development of cancer drug, in particular, the development of novel 1,2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof.
2. Description of the Prior Art
Telomere
A telomere is a
1, 2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to development of cancer drug, especially relates to the development of novel 1,2-disubstituted amido-anthraquinone derivatives, preparation method and application thereof.
2. Description of the Prior Art
Telomere
A telomere
1,4-bis-(amino-hydroxyalkylamino)-anthraquinones for inhibiting protein kinase C
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FIELD OF THE INVENTION
The present invention relates to the field of treatments for inflammatory and cardiovascular diseases, and chemotherapeutic agents. More particularly, the present invention relates to novel 1,4-bis-(amino-hydroxylalkylamino)-anthraquinones for inhibiting the enzyme protein
Bis-(hydroxyalkylamino)-anthraquinone inhibitors of protein kinase C
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FIELD OF THE INVENTION
The present invention relates to the field of treatments for inflammatory and cardiovascular diseases, and chemotherapeutic agents. More particularly, the present invention relates to novel asymmetric 1,4-bis-(amino-hydroxylalkylamino)-anthraquinones for inhibiting the enzyme
Method of treating tumors in warm-blooded animals
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BRIEF SUMMARY OF THE INVENTION
This invention relates to novel compositions of matter useful for ameliorating cancer diseases in mammals. More particularly, it relates to therapeutic compositions of matter containing certain symmetrical 1,4-bis(substituted-amino)anthraquinones or the non-toxic
Synthesis and use of anti-tumor drug LQC-Y
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TECHNICAL FIELD
The present invention relates to chemistry and bioscience filed, and specifically relates to LQC-Y general structural formula and the synthesis and the use thereof. It is proved by pharmacological experiments that this kind of compounds have a notable anti-tumor effect. No toxic
1-(Aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones
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BRIEF SUMMARY OF THE INVENTION
This invention relates to new organic compounds and, more particularly, is concerned with novel 1-(aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones which may be represented by the following general formula: ##STR1## wherein n is an integer from 2 to 4,
1-(Aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones
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BRIEF SUMMARY OF THE INVENTION
This invention relates to new organic compounds and, more particularly, is concerned with novel 1-(aminoalkylamino)-5,8-dihydroxy-4-substituted-anthraquinones which may be represented by the following general formula: ##STR1## wherein Z is hydroxy or monoalkylamino
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