aortic valve insufficiency/potássio

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[Myocardial protection with cold blood potassium cardioplegia in aortic regurgitation].

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Surgery for ascending aortic aneurysm with aortic regurgitation.

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We reviewed 22 consecutive patients undergoing surgery during 13 years from 1968 to 1981 for ascending aortic aneurysms associated with aortic regurgitation due primarily to idiopathic medionecrosis resulting in annuloaortic ectasia. Chronic aortic dissection was accompanied in 45% of the patients.

Echocardiography in chronic aortic insufficiency. Is valve replacement too late when left ventricular end-systolic dimension reaches 55 mm?

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To determine whether a ventricular (LV) end-systolic dimension (ESD) greater than or equal to 55 mm and LV left fractional shortening less than 25% are risk factors for aortic valve replacement (AVR) in patients with aortic insufficiency, we analyzed the clinical course and M-mode echocardiograms in

[Pathomorphological and morphometric evaluation of a model of aortic insufficiency in rabbits treated with taurine].

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In 45 experimental rabbits, subjected to trans-carotid aorto-valvulotomy in a month developed a congestive heart failure. When this group of rabbits was compared to the control group of 20 animals, in the course of complete pathomorphologic, histochemical and stereomorphologic analysis the following

Angiotensin AT1 receptor-mediated attenuation of cardiac hypertrophy due to volume overload: involvement of endothelin.

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The role of angiotensin II via the angiotensin type 1 (AT1) receptor in the development of volume overload cardiac hypertrophy was investigated in adult male Wistar rats with aortic insufficiency. We examined the effects of specific angiotensin AT1 receptor blockade with losartan

Surgical treatment of annuloaortic ectasia.

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Twenty-two patients with annuloaortic ectasia (an aneurysm of the ascending aorta and aortic valve incompetence) due to cystic medionecrosis underwent surgical repair between 1967 and 1979. Twelve patients had Marfan's syndrome and 4 had a forme fruste. The use of a valved conduit and improved

Upregulated Na/Ca exchange is involved in both contractile dysfunction and arrhythmogenesis in heart failure.

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Systolic heart failure (HF) is characterized by reduced systolic function and often by arrhythmias. We studied a rabbit model of HF (induced by combined aortic insufficiency and stenosis) which shows both contractile dysfunction and arrhythmogenesis. In this model we find an approximately 100%

Multicentre investigation of myocardial protection with cold cardioplegia.

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In order to analyze factors of importance for the efficiency of myocardial protection during open-heart surgery, a study was made of 144 patients undergoing isolated aortic valve replacement with various cardioplegic techniques. The cardioplegia was of Bretschneider type in 54 cases, St Thomas in 31

Mechanical restitution of isolated human ventricular myocardium subjected to in vivo pressure and volume overload.

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OBJECTIVE The aim was to make a comparison of the mechanical and electrical refractory properties of isolated strips of human ventricular myocardium obtained from patients with either left ventricular pressure overload, volume overload, or normal left ventricular function. METHODS Strips of

Clinical assessment of prolonged myocardial preservation for patients with a severely dilated heart.

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BACKGROUND The purpose of this study was to compare the myocardial protective effect of histidine-tryptophan-potassium and glucose-insulin-potassium cardioplegic solutions in patients with a dilated heart (left ventricular diastolic diameter > 55 mm, left ventricular systolic diameter > 45 mm)

Hypokalemic paralysis and osteomalacia secondary to renal tubular acidosis in a case with primary Sjögren's syndrome.

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A 39-year-old Japanese woman was admitted to our hospital for severe weakness owing to potassium deficiency caused by type 1 renal tubular acidosis (RTA1). Sicca complex, serological tests, and lip biopsy revealed that she had Sjögren's syndrome (SS). Acidosis was corrected by alkali supplement

Left ventricular function following aortic valve replacement: assessment by radionuclide ventriculography.

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Left ventricular function following aortic valve replacement has been evaluated in 15 consecutive patients. Cold potassium cardioplegia was utilized for myocardial preservation. Left ventricular function was assessed by radionuclide ventriculography performed preoperatively and 3 months

Correlation of degree of left ventricular volume overload with clinical course in aortic and mitral regurgitation.

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The results of left ventricular volume studies using biplane angiocardiography are described in 20 patients with mitral regurgitation and in 27 patients with aortic regurgitation. In both lesions, a regurgitant fraction of over 60 per cent was likely to be associated with severe symptoms and most

Remodelling and functional alterations of the rabbit coronary artery in volume overloaded heart.

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OBJECTIVE The aim was to study the contractility of the conduit coronary artery to vasoactive agents in developing and established volume overload cardiac hypertrophy and to compare it with structural alterations in the artery. METHODS Aortic valve insufficiency in rabbits was used to produce a

Genuine effects of ventricular fibrillation upon myocardial blood flow, metabolism and catecholamines in patients with aortic stenosis.

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OBJECTIVE Ventricular fibrillation (VF) is life-threatening because of its haemodynamic and metabolic effects. The purpose was to examine if VF also has primary effects per se. We therefore investigated the early effects of VF on myocardial blood flow, metabolic characteristics and catecholamine

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