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atherosclerosis/albumina

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Introduction Malignancies during childhood constitute the 2nd cause of death, following injuries worldwide. According to epidemiological data, 300,000 new cases of neoplasia present themselves every year in children and teenagers under 19 years of age1, 160,000 of which concern children under the

Periodontitis and Atherosclerotic-related Arterial Stenosis

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Periodontitis has been demonstrated as a risk factor for ischaemic stroke in several clinical studies. Atherosclerosis of the cerebral vasculatureis an important pathological process causing ischaemic stroke. The investigator's study aims to investigate the relationship between tooth loss(used as a

The Immune System in End Stage CKD Patients - Comparison Among Different Modalities of RRT

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The sustained inflammatory state in CKD is of complex pathogenesis and is believed to be in part attributable to the augmented activation of innate immune system cell subsets. The activation of the innate immune system plays an essential role within all the spectrum of cardiovascular disease in CKD,

Arterial Composition and Cardiovascular Outcome in DIabeteS

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PhD project description The arterial wall in patients with diabetes: Do changes in arterial basement membrane proteins predict future arterial disease? Are remodeling processes altered? Applicant: Anne-Sofie Faarvang Thorsen1, MD Main supervisor: Professor Lars Melholt Rasmussen1 Co-supervisors:

Effect of Rosuvastatin on the Clinical Features of Preeclampsia

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Preeclampsia is a multisystem disorder that complicates 3-5% of pregnancies and remains a major cause of maternal, fetal, and neonatal morbidity and mortality.(1) Preeclampsia is characterized by the development of new onset hypertension (HTN) and the establishment of proteinuria. Other signs and

Impact of Vitamin D Supplementation on Cardiometabolic Status and Androgen Profile in Polycystic Ovary Syndrome

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Background Polycystic ovarian syndrome (PCOS) is a heterogeneous disorder affecting 510% of women of reproductive age. It is a disorder that affects the reproductive, endocrine and metabolic functions and is the leading cause of chronic anovulation leading to infertility. PCOS is characterized by

The Effect of High-flux Hemodialysis and On-line Hemodiafiltration on Endothelial Function.

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The main aim of this project is to evaluate, in patients with chronic kidney disease (CKD5D), the role of adhesion molecules in leukocyte adhesion and transendothelial migration involved in atherogenesis. This trial is a prospective randomized crossover study in CKD5D hemodialysis patients followed

The Effect of Childhood Dyslipidemia on Endothelial and Renal Function

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In children recruited in the study, family history of dyslipidemia or premature cardiovascular disease will be recorded. Furthermore, anthropometric and clinical characteristics will be noted and lipid measurements will be obtained at recruitment after a fasting period. The investigators will test

Muscle Mass or Muscle Function as a prédictive Tools for Outtcomme in Chronic Dialysis Patients

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Aim of this study is to compare the association of muscle mass and functionality with mortality among chronic haemodialysis - the involvement of malnutrition inflammation and atherogenesis syndrome (increase in C reactive protein and decrease in serum albumin) on voluntary muscle strength impairment

Magnesium Supplementation in Diabetic Nephropathy

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Diabetic nephropathy is a serious kidney-related complication of type 1 diabetes and type 2 diabetes. It is also called diabetic kidney disease. Up to 40 percent of people with diabetes eventually develop kidney disease. Over time, elevated blood sugar associated with uncontrolled diabetes causes

Markers of Vascular Calcification in Diabetic Nephropathy in Patients With Diabetic Nephropathy

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Osteopontin (OPN) is one of integrin-binding N-linked glycoproteins, which is produced by activated mononuclear cells and is linked to increasing evidence about the role of OPN in vascular calcification[1]. Recent clinical studies have shown that vascular calcification is a pathological process

Allopurinol in Diabetes Mellitus and Multivessel Coronary Artery Disease

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This is a pilot study, PROBE design (prospective randomized open label blinded endpoints study), that will include 100 patients. Patients will be recruited during their hospitalization in the cardiology department of Ichilov- Tel-Aviv Sourasky Medical Center. It will include patients with known or

ZIMBA: Clinical Trial in Paediatric Obesity

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Study design: A single-center pilot open-label randomized control trial. Population: The study will comprise a total of 60 subjects of both sexes, with pubertal stage ≥ 3 according to the Tanner stage, obese according to the IOTF criteria (International Obesity Task Force), diet naïve or with

The ILERVAS Project: Assessing the Prevalence of Subclinical Vascular Disease and Hidden Kidney Disease

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STUDY DESIGN AND POPULATION: Randomized interventional study. From 2015 to 2018, 16,660 participants (8,330 in the intervention group (Mobile Unit Follow-up Group) and 8,330 in the no intervention group (Electronic Medical History Follow-up Group)) aged between 45 and 70 years without a previous

Characterization of Removal Capacities of the Theranova Membrane by Proteomic Investigations

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