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We report a 31-year-old man with a bronchogenic type of congenital esophageal cyst, which was discovered in the course of diagnostic evaluation for thoracic back pain, fever, and diarrhea. He was treated successfully by surgical excision of the cyst. The embryology, classification, and symptoms of
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OBJECTIVE
Buprenorphine HCl buccal film has been developed for treating chronic pain utilizing BioErodible MucoAdhesive (BEMA(®)) delivery technology. Buccal buprenorphine (BBUP; Belbuca(TM), Endo Pharmaceuticals) was evaluated for the management of moderate to severe chronic low back pain (CLBP)
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A 50-year-old female patient complained about watery diarrhea for two weeks. Because of back pain nonsteroidal antirheumatics had been prescribed for months before. The endoscopic and radiologic investigation demonstrated a large gastrocolic fistula due to NSAID-induced gastric ulceration and an
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Opioids have been used for centuries, mostly as a sedative and to treat pain. Currently, they are used on a global scale for the treatment of acute and chronic pain in diseases as osteoarthritis, fibromyalgia, and low back pain. Binding of opioids on opioid receptors can cause a range of different
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BACKGROUND
This study evaluated the safety and efficacy of tramadol ER 300 mg and 200 mg versus placebo once daily in the treatment of chronic low back pain, using an open-label run-in followed by, without washout, a randomized controlled study design.
METHODS
Adults with scores > or = 40 on a pain
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This study assessed the potential effects of age, sex, and prior opioid use on the response to oxymorphone extended release (ER) in patients with moderate to severe chronic low back pain.
METHODS
Combined data from 2 placebo-controlled clinical trials with an enriched-enrollment,
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Twenty-eight outpatients with chronic severe lumbar pain participated in a double-blind comparative trial on the clinical efficacy of orally administered piroxicam and indomethacin. Half of the patients received indomethacin, 25 mg t.i.d.; the other half received piroxicam 20 mg in the morning and a
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This open-label, phase 3b study evaluated the effectiveness and tolerability of tapentadol prolonged release and tapentadol immediate release (for acute pain episodes) for severe, chronic low back pain with or without a neuropathic pain component that was inadequately managed in patients
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METHODS
This was a randomized, double-blind, placebo-controlled clinical trial.
OBJECTIVE
To assess the efficacy and safety of duloxetine in the treatment of chronic low back pain (CLBP).
BACKGROUND
Imbalance of serotonin and norepinephrine within modulatory pain pathways has been implicated in the
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Fulranumab is an investigational, fully human recombinant monoclonal antibody (IgG2) that neutralizes the biological actions of human nerve growth factor. Low back pain is a common cause of noncancer chronic pain and represents one of the most significant socioeconomic health-related problems in
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BACKGROUND
Tarlov cysts (TCs) are expanded nerve root sheaths that occur near the dorsal root ganglion and result from increased intraspinal hydrostatic pressure. TCs most frequently affect the lumbosacral plexus and therefore may cause specific symptoms such as perineal pain and neurogenic bladder,
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A 61-year-old former postal worker presented with progressive pain in his lower back, weakness in his right leg, and numbness in his left foot. In recent weeks, he had dragged his right leg in order to walk. He had also had intermittent diarrhea and dysuria but no hematuria or weight loss.
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OBJECTIVE
Irritable bowel syndrome (IBS) is a common functional bowel disease in the West. Information on the prevalence of IBS in the Asian population is relatively scanty. The aims of the present study were to determine the prevalence of IBS and to assess the symptom subgroups based on the
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