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begonia kingdon-wardii/cancro
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Cytotoxic and anti-HIV principles from the rhizomes of Begonia nantoensis.
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Three new compounds: begonanline (1). nantoamide (2). and methyl (S)-glycerate (3). as well as forty-four known compounds have been isolated and characterized from the rhizomes of Begonia nantoensis. The structures of these compounds were determined by spectral analyses and/or X-ray crystallography.
Cucurbitacins: differential cytotoxicity, dereplication and first isolation from Gonystylus keithii.
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A characteristic pattern of differential cytotoxicity of extracts of Iberis amara seeds, predominantly toward renal tumor, brain tumor, and melanoma cell lines in the NCI human disease-oriented tumor screening panel, was traced to cucurbitacins E [1] and I [2]. This same differential cytotoxicity
Antifungal compounds with anticancer potential from Trichoderma sp. P8BDA1F1, an endophytic fungus from Begonia venosa.
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Fungi in the genus Trichoderma are notorious producers of secondary metabolites with diverse applications, such as antibacterial, antifungal, and plant growth-promoting properties. Peptaibols are linear peptides produced by such fungi, with more than 440 compounds described to date, including
Phytochemical and biological investigation of Begonia heracleifolia.
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From the rhizomes of Begonia heracleifolia six known cucurbitacins ( 1- 6) were isolated. Based on spectral data (1D and 2D (1)H-, (13)C-NMR, ESI- and CI-MS) the structures were established as cucurbitacin B ( 1), cucurbitacin D ( 2), 23,24-dihydrocucurbitacin D ( 3), 23,24-dihydrocucurbitacin F (
A new steroid glycoside from Begonia sp.: cytotoxic activity and docking studies.
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Chemical investigation on the ethyl acetate extract of the aerial parts of Begonia sp. afforded a new steroid glycoside, 9(11)α,16(17)α-dioxirane-20,25-dihydroxy-β-sitosterol-3-O-β-glucopyranoside (1) along with a known steroidal glycoside,
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