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benzopyrone/hipersensibilidade
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4 resultados
Synthesis and pharmacological study of new N-methyl 1,2,3-triazole derivatives of 2-cyano chromones.
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The reaction of various 2-cyano chromones with diazomethane generated a series of 21 N-methyl triazoles, with a benzopyrone moiety and divided into three isomeric groups. The anti-inflammatory, psychotropic and anti-allergic effects of these new compounds were evaluated. The results obtained did not
Photosensitization by coumarin derivatives.
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Coumarin and several of its derivatives were investigated for their photosensitizing properties. With a few exceptions, the coumarins are potentially strong photocontact sensitizers but do not evoke phototoxic reactions. Substitution at the 6 or 7 positions of the benzopyrone ring confers
Phase II study of coumarin and cimetidine in patients with metastatic renal cell carcinoma.
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Fifty patients with locally advanced or metastatic renal cell carcinoma were treated with coumarin (1,2-benzopyrone) at 100 mg orally daily starting on day 1 and cimetidine 300 mg orally four times a day starting on day 15. When disease progressed, coumarin was escalated to 100 mg orally four times
Anti-inflammatory properties of dietary flavonoids.
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Flavonoids are a group of natural substances that are located in sources of vegetal origin. More than 4,000 varieties of flavonoids have been identified. All of them are phenyl-benzopyrones of low molecular weight with a basic structure formed by two benzene rings united through a heterocyclic
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