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Scopolamine treatment for severe extra-pyramidal signs following organophosphate (chlorpyrifos) ingestion.

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BACKGROUND The use of competitive inhibitors of acetylcholine other than atropine, for patients with organophosphate poisoning is controversial. Because scopolamine ability to cross the blood-brain barrier is better than that of atropine, it has been suggested that it should be used in patients with

Withdrawal symptoms after discontinuation of transdermal scopolamine therapy: treatment with meclizine.

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OBJECTIVE The case of a patient who treated withdrawal symptoms from trans-dermal scopolamine with meclizine is reported. CONCLUSIONS A 30-year-old woman for whom transdermal scopolamine was prescribed to manage motion sickness during a vacation experienced severe withdrawal symptoms that began 24

[Chronic myelogenous leukemia complicated by drug-induced agranulocytosis].

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We describe a patient with chronic myelogenous leukemia (CML) who developed drug-induced agranulocytosis. A 75-year-old female was diagnosed with CML in December 2001. She had been receiving imatinib therapy for more than five years. In August 2007, she was hospitalized due to a severe neutropenia

Oesophageal spasm, vomiting and hyoscine hydrobromide patch.

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We report the case of a 60-year-old woman with metastatic breast cancer whose intractable nausea and vomiting were effectively managed with a hyoscine hydrobromide (scopolamine) patch. Contrast swallow revealed oesophageal spasm to be the underlying cause. Symptom relief may be attributed to the

Noninfectious crystalline keratopathy after postoperative subconjunctival 5-fluorouracil.

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OBJECTIVE To describe a case of transient, noninfectious crystalline keratopathy after postoperative subconjunctival 5-fluorouracil. METHODS Case report. Slit-lamp biomicroscopic examinations were performed during serial office examinations. RESULTS A 69-year-old woman underwent an uncomplicated

Choledocholithiasis in an infant of extremely low birthweight.

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A five-month-old infant of extremely low birthweight with choledocholithiasis is reported. A baby girl was delivered at 26 weeks gestation as a second twin, weighing 834 g. At 30 days of age, gallbladder stones were found by routine ultrasonography. She had vomiting at 157 days of age.

Atropa belladonna intoxication: a case report.

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Atropa belladonna is a poisonous plant also called deadly nightshade. Its roots, leaves and fruits contain alkaloids: atropine, hyocyamine and scopolamine. The risk of poisoning in children is important because of possible confusion with other berries. Atropa belladonna acute intoxication is a

[Analytical investigation of a suspected case of drug-facilitated crime].

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Sometimes it is suspected that people have been involuntary exposed to drugs, usually by spiked drinks. A young woman was transported to an emergency department by ambulance. Her clinical symptoms (decreased consciousness, mydriasis, confusion, hallucinations and urine retention) indicated

Acute deterioration of bulbar function after botulinum toxin treatment for sialorrhoea in amyotrophic lateral sclerosis.

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Transcutaneous botulinum toxin injection in the salivary glands was introduced in 2000 as a new treatment for sialorrhoea in amyotrophic lateral sclerosis (ALS). We describe an ALS patient who developed serious complications of botulinum toxin treatment for sialorrhoea, and we review the relevant

Unknowing ingestion of Brugmansia suaveolens leaves presenting with signs of anticholinergic toxicity: a case report.

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Brugmansia suaveolens is the commonest species under the Solanacea ("Angels Trumpet" in English; "Attana" in Sinhalese) plant family in Sri Lanka. It contains alkaloids like scopolamine, atropine and hyoscyamine which can cause an anticholinergic toxindrome. There

[Akiko Yosano, the famous Japanese poet and writer, is the first lady who experienced labor analgesia in Japan?].

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There have been some records of labor analgesia with intravenous or rectal anesthetics since 1925. It is widely believed that labor epidural analgesia in Japan started to become popular after the World War II (1939-1945). However, the author found that Akiko Yosano, a well-known Japanese female poet

Effects of remifentanil on the sphincter of Oddi in a 3-year-old child: a case report.

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Opioids cause spasm of the sphincter of Oddi. Remifentanil is metabolized enzymatically throughout the body. Its context-sensitive half-time is 3 to 4minutes. The effect of remifentanil on the sphincter of Oddi is unknown, especially in children. We recently encountered a patient in whom the

[Acute Datura stramonium poisoning in an emergency department].

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BACKGROUND The toxic effects of Datura stramonium most often include visual and auditory hallucinations, confusion and agitation. Severe and even fatal complications (coma, respiratory distress or death in more than 5% of cases) are not rare since the lethal concentration of the drug's toxic

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