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Pain, Nutrition and Glycemic Response in Chronic Low Back Pain and Breast Cancer Survivors

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Study Design: This study will be carried out as an experimental, cross-over study, including two pain populations, one control group and two assessment sessions. At the first session, firstly, all participants will undergo an assessment including pain-related outcomes, nutrition-related outcomes,

Early Environmental and Maternal Determinants of Airway Inflammation in Wheezing Disorders in Infants

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Background: Lung development and growth is a complexly orchestrated process starting prenatally in the first embryonic weeks, and ending, with the last important stages of alveolarization from the 24th week onwards. By the time of birth, around one third of the total amount of alveoli has developed,

Level of FeNO in Chinese Asthma Patients

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Introduction Measurement of fractional nitric oxide (NO) concentration in exhaled breath (FeNO) has been shown to be a non-invasive, quantitative biomarker related to airway inflammation. Although there is inadequate evidence to support the use of FENO to aid the diagnosis of asthma, recent studies

'MyPinkMom' Educational Intervention for Pregnant Women With Anaemia

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General objective: To assess the effectiveness of 'MyPinkMom' educational intervention in terms of knowledge on anaemia in pregnancy, Theory of Planned Behaviour (TPB) construct to adherence of daily iron tablet intake, haemoglobin level, and dietary iron intake among pregnant women with anaemia in
Background: Cystic fibrosis (CF) is the most common lethal inherited disease in North European populations, affecting approximately 1:2500 live births. It is a multisystem disorder with respiratory morbidity and mortality being the leading cause of death. Lung disease in CF is characterized by

Hypertension Management in Cancer Patients

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This is a 12-week prospective study with two phases. In Phase 1 (Weeks 1-4), participants will self-monitor their blood pressure using the Qardio bluetooth device. In Phase 2 (Weeks 5-12), the investigators will implement the auto-messaging system triggered by a weekly average systolic blood

Protocol PERCAF 2018

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Coffee is the most consumed arousing substance in the world. Caffeine is used as a natural countermeasure to maintain the performance of sleep deprived subjects. However, the effectiveness of caffeine is characterized by a large individual variability, also observed on side effects. This variability
The World Health Organisation (WHO) has deemed being overweight or obese as the fifth leading cause for global deaths, with more than 1.9 billion adults being defined as overweight, and 600 million defined as being obese. Conditions associated with obesity, such as stroke, type 2 diabetes, certain

Efficacy of Zinc on Concurrent Chemo-radiotherapy Induced Taste Alterations

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Consecutive Sampling was used. It was a two-stage sampling method. Data was collected from patients visiting the Oncology Section at Atomic Energy Medical Centre Karachi from September 2017 to March 2018 on a proforma after being examined by the section head oncologist for the tumor. A standard

Molecular Imaging of Pituitary Adenomas

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Aim: In this proof-of-concept study, the investigators will seek to establish whether imaging changes in Dopaminergic transmission and receptor function has the potential to improve localisation and management of pituitary adenomas. Methods: Patients will be recruited from the general endocrine and

Evaluation of a Supplement for Weight Management in Obese and Overweight Individuals

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The present study is a randomized double-blind placebo controlled repeated measures design, with sampling of the cohorts on five separate occasions. Group 1: Intervention Group (n = 24) Healthy, overweight or obese physically inactive males, supplement, n = 12 Healthy, overweight or obese physically

Nicotinamide Riboside on Mitochondrial Function in Li-Fraumeni Syndrome

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We have previously reported that inherited mutations of TP53, which causes the premature cancer disorder Li-Fraumeni syndrome (LFS), can promote mitochondrial function both in patients and mouse models. In the course of our follow up studies, we encountered a LFS patient with a long-standing history

Using Imaging to Assess Effects of THC on Brain Activity

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Marijuana has become the most popular illicit drug in the western world (Substance Abuse and Mental Health Services Administration, 2004). Both acute and chronic exposure to cannabis is associated with changes in brain activity in frontal, limbic and also cerebellar regions, with generally increased
Oral cancer is the sixth most common cancer in males and the twelfth most common in females. Approximately, 94% of all oral malignancies are squamous cell carcinoma. Over the past few decades, researchers have explored alternate therapies and remedies to prevent its progression but have yielded to
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