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Military Alerting System for Monitoring Body Temperature During Active Cooling

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The study will be completed in the following timeline: Visit 1: Baseline and VO2max Testing Visit 2-4: Trial 1, 2 and 3 Visit specific information is described below, however, specific data collection protocols for dependent variables and procedures are included below the description of the study

Population at Risk of Malignant Hyperthermia: Ambispective Cohort.

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Malignant hyperthermia (MH) is a pharmacogenetic disease that manifests itself as a hypermetabolic response of skeletal musculature, in genetically susceptible patients, with the inhalation of volatile halogenated anesthetics, depolarizing neuromuscular relaxants such and, rarely, physical stressors

Oral Dextrose Formula in Performance of Soccer Athlete

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Male academy soccer players, included in a trial, received two types of solutions (compound of 150 cc dextrose 10% + 20 mM sodium or single 150 cc dextrose 10%) interchangeably, separated within 120 minutes were completed in a counterbalanced, randomized, double-blind, crossover design. The study

Cryo Pack Cooling After Exercise-induced Hyperthermia

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This study will consist of three study visits: Visit 1: Baseline and VO2max Testing Visit 2-3: Trial 1 and 2. Visit 1: Baseline and VO2max Testing Participants who are approved to participate will be scheduled for a baseline and VO2max testing day. Upon arrival to the lab, subjects will provide a

RCT of SPG Blocks for Post-dural Headache

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The postdural puncture headache (PDPH) is a well-documented complication of dural puncture. Depending on a number of factors, the overall incidence of PDPH following unintended dural puncture with an epidural placement needle is typically around 50%, but can be as high as 70% for certain

Fructose and Glucose and TAS1R2 in Type 1 Diabetes

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INTRODUCTION: Fructose is transported via the portal vein to the liver, where is rapidly taken up by hepatocytes and phosphorylated to fructose-1-phosphate independent of insulin action by the enzyme fructokinase. Thus, under normal conditions, fructose is converted mainly to glucose, glycogen, and

A Study to Assess the Efficacy and Safety of Fospropofol Disodium

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After local ethics committee (West China Hospital, Sichuan University, Chengdu, China) approval and written informed consent were obtained, 80 healthy volunteers (40 males and 40 females) aged between 18 and 45 yr were included. For 1 week before the study, subjects were to follow a diet with

Effect of Combined Exercise, Heat, and Quercetin Supplementation on Whole Body Stress Response

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Overall Protocol: This study will involve a repeated-measures design (2 conditions) in which subjects will perform exercise in the heat. Each condition will begin with an Intestinal Permeability Measurement (IP1), where subjects will be admitted to the General Clinical Research Center (GCRC),

A Drug Interaction Study of Valproic Acid and Single-dose Paliperidone Extended-Release (ER) in Healthy Men

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This is an open-label (patient will know the identity of the study drug they are taking) study in healthy volunteers (only healthy men will be asked to participate in the study). The primary purpose of the study is to determine how paliperidone (a schizophrenia medication) and divalproex sodium (an
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