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colitis/tyrosine

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9 resultados

Homopiperazine derivatives as protein tyrosine kinase inhibitors and pharmaceutical use thereof

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FIELD OF THE INVENTION This invention relates to compounds which are inhibitors of protein tyrosine kinases, such as the Janus kinases, and to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases comprising administering to a

Sulfamide piperazine derivatives as protein tyrosine kinase inhibitors and pharmaceutical use therof

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FIELD OF THE INVENTION This invention relates to compounds which are inhibitors of protein tyrosine kinases, such as the Janus kinases, and to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases comprising administering to a

Heterocyclic compounds as JAK receptor and protein tyrosine kinase inhibitors

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FIELD OF THE INVENTION This invention relates to compounds which are inhibitors of protein tyrosine kinases, such as the Janus kinases, and to said compounds for use in therapy, to pharmaceutical compositions comprising said compounds, to methods of treating diseases comprising administering to a

Pyrazole derivatives as p38 MAP inhibitors

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FIELD OF THE INVENTION The invention relates to compounds which are inhibitors of the family of p38 mitogen-activated protein kinase enzymes (referred to herein as p38 MAP kinase inhibitors), particularly the alpha sub-type thereof, and of Syk kinase and the Src family of tyrosine kinases, and to

Monocyclic-7H-pyrrolo[2,3-d]pyrimidine compounds, compositions, and methods of use

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BACKGROUND OF THE INVENTION The present invention relates to pyrrolo[2,3-d]pyrimidine compounds which are inhibitors of protein tyrosine kinases, such as the enzyme Janus Kinase 3 (hereinafter also referred to as JAK3) and as such are useful therapy as immunosuppressive agents for organ transplants,

Pyrrolo[2,3-d]pyrimidine compounds

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Entrar Inscrever-se
BACKGROUND OF THE INVENTION The present invention relates to pyrrolo[2,3-d]pyrimidine compounds which are inhibitors of protein tyrosine kinases, such as the enzyme Janus Kinase 3 (hereinafter also referred to as JAK3) and as such are useful therapy as immunosuppressive agents for organ transplants,

Pyrrolo[2,3-d]pyrimidine compounds

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Entrar Inscrever-se
BACKGROUND OF THE INVENTION The present invention relates to pyrrolo[2,3-d]pyrimidine compounds which are inhibitors of protein tyrosine kinases, such as the enzyme Janus Kinase 3 (hereinafter also referred to as JAK3) and as such are useful therapy as immunosuppressive agents for organ transplants,

Pyrrolo [2,3-D] pyrimidine compounds

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Entrar Inscrever-se
BACKGROUND OF THE INVENTION The present invention relates to pyrrolo[2,3-d]pyrimidine compounds which are inhibitors of protein tyrosine kinases, such as the enzyme Janus Kinase 3 (hereinafter also referred to as JAK3) and as such are useful therapy as immunosuppressive agents for organ transplants,

Pyrrolo[2,3-d]pyrimidine compounds

Apenas usuários registrados podem traduzir artigos
Entrar Inscrever-se
BACKGROUND OF THE INVENTION The present invention relates to pyrrolo[2,3-d]pyrimidine compounds which are inhibitors of protein tyrosine kinases, such as the enzyme Janus Kinase 3 (hereinafter also referred to as JAK3) and as such are useful therapy as immunosuppressive agents for organ transplants,
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