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Lobular breast cancer--the most common special subtype or a most special common subtype?
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Lobular breast cancer is not only the second most common breast cancer subtype, known for decades, but also a tumour entity that still poses many unresolved questions. These include questions about the targets and cooperation partners of E-cadherin, the best model systems for translational research,
Common variable immunodeficiency and breast cancer.
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We describe two women with early onset breast cancer (at ages 31 and 38) who were found to have common variable immunodeficiency (CVID). Both women had a history of frequent and unusual bacterial infections. The incidence of breast cancer in young women and of CVID are both low, and the coincident
Common threads in breast cancer proteomes.
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Common cytogenetic findings in primary breast cancer.
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Five cases of breast cancer were cytogenetically studied by G-banding, using direct tumor preparations. Chromosomes involved in aberrations, according to frequency, were #1, #11, #3, #6, #5, and #17. In all five cases there were abnormalities of chromosomes #1 and #11. In each case chromosome #1 was
Common susceptibility loci for male breast cancer
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Background: The aetiology of male breast cancer (MBC) is poorly understood. In particular, the extent to which the genetic basis of MBC differs from female breast cancer (FBC) is unknown. A previous genome-wide association study (GWAS) of
Breast cancer is the most common cancer.
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Breast cancer--answers to some common questions.
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Prognosis of common cancers.
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Four cancers in each sex account for nearly 60% of all cases. Lung cancer therapy is stymied by a lack of effective agents, but can be prevented by a smoking cessation program. Breast cancer is far too prevalent, but has the best response rate to drugs and the best palliation of any of these
Use of common medications and breast cancer risk.
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Prescription and over-the-counter medications are widely used in the United States and many western countries. More than two-thirds of women ages >45 years, who are at greatest risk for breast cancer, take prescription medication. In light of the ubiquitous nature of medication use and the fact that
The influence of common polymorphisms on breast cancer.
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Breast cancer is one of the most frequently diagnosed cancers in the Western world and a significant cause of mortality worldwide. A small proportion of cases are accounted for by high-penetrance monogenic predisposition genes; however, this explains only a small fraction (less than 5%) of all
Breast cancer screening: science, society and common sense.
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Most common breast cancer drops a dramatic 15%.
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Cadherin-11 in poor prognosis malignancies and rheumatoid arthritis: common target, common therapies.
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Cadherin-11 (CDH11), associated with epithelial to mesenchymal transformation in development, poor prognosis malignancies and cancer stem cells, is also a major therapeutic target in rheumatoid arthritis (RA). CDH11 expressing basal-like breast carcinomas and other CDH11 expressing malignancies
Common germline polymorphisms associated with breast cancer-specific survival.
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BACKGROUND
Previous studies have identified common germline variants nominally associated with breast cancer survival. These associations have not been widely replicated in further studies. The purpose of this study was to evaluate the association of previously reported SNPs with breast
Breast cancer. Part 1: Awareness and common benign diseases.
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Breast cancer is the most common cancer for women in the United Kingdom and topic on which there is much information. This article discusses the principles behind breast awareness and breast health, detailing common benign breast diseases that cause disproportionate anxiety. The NHS Breast Screening
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