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common/triglyceride
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The common biological basis for common complex diseases: evidence from lipoprotein lipase gene.
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The lipoprotein lipase (LPL) gene encodes a rate-limiting enzyme protein that has a key role in the hydrolysis of triglycerides. Hypertriglyceridemia, one widely prevalent syndrome of LPL deficiency and dysfunction, may be a risk factor in the development of dyslipidemia, type II diabetes (T2D),
Triglyceride glucose index and common carotid wall shear stress.
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OBJECTIVE
Alterations in wall shear stress contribute to both clinical and subclinical atherosclerosis. Several conditions such as hypertension, diabetes, and obesity can impair shear stress, but the role of insulin resistance has never been investigated. The present study was designed to
Lipoprotein lipase deficiency--rare or common?
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Cardiovascular disease is the number one killer in the world. Prevention is the most promising treatment. However, predicting an individual's risk for cardiovascular disease is quite complicated, involving the complex interaction of a plethora of environmental and genetic factors. Many of the
Common etiologies of neonatal pleural effusion.
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BACKGROUND
Pleural effusion is rare and includes several disease entities in the neonatal period. The aim of this study was to investigate the etiology, management, and outcome of neonatal pleural effusions.
METHODS
We retrospectively collected all neonates who were admitted to the neonatal
Gout and diabetes: a common combination.
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The aims of this cross-sectional study were to compare metabolic parameters in people with gout and diabetes with gout only and type 2 diabetes mellitus (T2DM) only. Fifty General Practices in NHS Ayrshire and Arran (population 340 377) contributed data. The sample was split into three groups, those
Genetic determinants of plasma triglycerides: impact of rare and common mutations.
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Raised plasma triglyceride (TG) levels are an independent risk factor for coronary artery disease (CAD), and thus understanding the genetic and environmental determinants of TG levels are of major importance. TG metabolism is a process for delivering free fatty acids for energy storage or
Dual analysis of triglycerides from certain common lipids and seed extracts.
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A number of reference oils, two commercial oils, and several oil extracts from seeds of Nicotiana species were analyzed for the fatty acid content and also for triglyceride composition. The seed oils were obtained using an accelerated solvent extraction procedure, which was proven to be very
A common mtDNA polymorphism associated with variation in plasma triglyceride concentration.
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Management of Hypertriglyceridemia: Common Questions and Answers
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Hypertriglyceridemia, defined as fasting serum triglyceride levels of 150 mg per dL or higher, is associated with increased risk of cardiovascular disease. Severely elevated triglyceride levels (500 mg per dL or higher) increase the risk of pancreatitis. Common risk factors for hypertriglyceridemia
Clinical chemistry of common apolipoprotein E isoforms.
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Apolipoprotein E plays a central role in clearance of lipoprotein remnants by serving as a ligand for low-density lipoprotein and apolipoprotein E receptors. Three common alleles (apolipoprotein E(2), E(3) and E(4)) give rise to six phenotypes. Apolipoprotein E(3) is the ancestral form. Common
Hypertriglyceridemia - Common Causes, Prevention and Treatment Strategies.
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BACKGROUND
Prevention and treatment of dyslipidemias represent the key issues of Cardiovascular Disease (CVD) prophylaxis. Consequently, the effective management of different types of lipid disorders, including hypertriglyceridemia, should be a priority for the healthcare practitioners (e.g.:
Common variants associated with plasma triglycerides and risk for coronary artery disease.
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Triglycerides are transported in plasma by specific triglyceride-rich lipoproteins; in epidemiological studies, increased triglyceride levels correlate with higher risk for coronary artery disease (CAD). However, it is unclear whether this association reflects causal processes. We used 185 common
Dipyrone interference on several common biochemical tests.
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We studied the effect in vitro and in vivo of dipyrone on the determination of several biochemical tests in two analyzers, a Hitachi 747 and a Kodak Ektachem 700. From studies in vitro, we found significant interference by dipyrone (P < 0.05) in the determination of creatine kinase (CK), lactate
Common sequence variant in lipoprotein lipase gene conferring triglyceride response to fibrate treatment.
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OBJECTIVE
Little is known about whether the variations in the lipoprotein lipase (LPL) and apolipoprotein gene cluster (APOA1/C3/A5) confer appreciable triglyceride lowering after fibrate treatment among patients with hypertriglyceridemia.
METHODS
We investigated whether variations in these genes
Lipid lowering effects of pravastatin in common marmosets.
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In the present study it was examined if the common marmoset was susceptible to pravastatin (CAS 81131-70-6, CS 514, Mevalotin), an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase. It has been reported that serum lipid levels in common marmosets resemble those in humans. First
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