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dementia/crise epiléptica
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Method of treating a human being for a class of neurological defects and seizure disorders
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BACKGROUND OF THE INVENTION
1. Field of Invention
This invention relates to treatment of human beings for conditions associated with deficiencies in the N-6-trimethyl-L-lysine (TML) pathway affecting biosynthesis of carnitine. Such conditions include: (1) seizures, myoclonic seizures, epilepsy,
Phenylpyrrole derivative
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CROSS REFERENCE TO RELATED APPLICATIONS
This application is a National Stage of International Application No. PCT/JP2012/081744 filed Dec. 7, 2012, claiming priority based on Japanese Patent Application No. 2011-268561 filed Dec. 8, 2011, the contents of all of which are incorporated herein by
Tetrahydropyridine-(or 4-hydroxypiperidine) alkylazoles
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The present invention relates to new 4-aryltetra-hydropyridines and 4-arylpiperidinols linked to alkyl-azoles of general formula (I) ##STR2##
and to their physiologically acceptable salts, to the processes for their preparation, to their application as medicaments and to the pharmaceutical
Use of isatin derivatives as ion channel activating agents
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TECHNICAL FIELD
The present invention relates to ion channel activating agents. More particularly, the present invention relates to a particular class of chemical compounds that has proven useful as openers of SK.sub.Ca and IK.sub.Ca channels. In further aspects, the present invention relates to the
Method of treating, preventing or inhibiting central nervous system injuries and diseases
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BACKGROUND OF THE INVENTION
1. Field of the Invention
The invention relates to a method of treating, preventing or inhibiting central nervous system (CNS) injuries and diseases. In particular, the invention relates to a method of treating, preventing or inhibiting a CNS injury or disease in a
Dimeric piperidine, tetrahydropyridine and piperazine derivatives
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This is a continuation of international application Ser. No. PCT/DK93/00198, filed Jun. 9, 1993 published as WO93/25527, Dec. 23, 1993.
The present invention relates to a novel class of dimeric piperidine, 1,2,3,6-tetrahydropyridine and piperazine derivatives in which the nitrogen atoms of the
Compositions and methods for the suppression of carbonic anhydrase activity
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PRIORITY
This application is a national phase filing of the Patent Cooperation Treaty (PCT) application # PCT/IB2013/050899 titled "COMPOSITIONS AND METHODS FOR THE SUPPRESSION OF CARBONIC ANHYDRASE ACTIVITY" filed on Feb. 3, 2013 Published with WIPO Publication # WO/2013/167994, which further
L-DOPA ethyl ester salts and uses thereof
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Throughout this application, various references are cited, using arabic numbers within parentheses. Full citations for these references can be found at the end of the specification, immediately preceding the claims. These publications, in their entireties, are hereby incorporated by reference into
Imidazoline compounds
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TECHNICAL FIELD
The present invention is useful in medical fields. In more detail, novel imidazoline compounds of this invention are useful as neuropeptide Y receptor antagonists and as agents for the treatment of various kinds of cardiovascular disorders, central nervous system disorders, metabolic
Imidazonline compounds
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This application is a 371 of PCT/JP01/01312 filed Feb. 22, 2001.
TECHNICAL FIELD
The present invention is useful in medical fields. In more detail, novel imidazoline compounds of this invention are useful as neuropeptide Y receptor antagonists and as agents for the treatment of various kinds of
Therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Piperazine Compounds, compositions comprising a Piperazine Compound and methods for treating or preventing a condition such as pain, urinary incontinence (UI), an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy,
Therapeutic agents useful for treating pain
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REFERENCE TO SEQUENCE LISTING SUBMITTED ELECTRONICALLY
The content of the electronically submitted Sequence Listing (Name: sequence_listing_ascii.txt; Size: 766 bytes; and Date of Creation: Mar. 19, 2012) filed herewith is incorporated herein by reference in its entirety.
1. FIELD OF THE
2-pyridinyl-1-piperazine therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Piperazine Compounds; compositions comprising a Piperazine Compound; and methods for preventing or treating pain, urinary incontinence (UI), an ulcer, inflammatory-bowel disease (IBD), irritable-bowel syndrome (IBS), an addictive disorder,
Therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Cycloheteroalkenyl Compounds, compositions comprising an effective amount of a Cycloheteroalkenyl Compound and methods for treating or preventing a condition such as pain comprising administering to an animal in need thereof an effective
Therapeutic agents useful for treating pain
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1. FIELD OF THE INVENTION
The present invention relates to Piperazine Compounds; compositions comprising a Piperazine Compound; and methods for preventing or treating pain, urinary incontinence (UI), an ulcer, inflammatory-bowel disease (IBD), irritable-bowel syndrome (IBS), an addictive disorder,
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