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Página 1 a partir de 1061 resultados
Challenges in the epidemiological investigation of the relationships between physical activity, obesity, diabetes, dementia and depression.
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There are many challenges facing epidemiologists wishing to investigate relationships between physical activity, obesity, diabetes, dementia and depression, all of which are complex fields in their own right. There is a large literature investigating the relationship between diabetes and dementia
Genetic risk of dementia modifies obesity effects on white matter myelin in cognitively healthy adults
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APOE-ε4 is a major genetic risk factor for late-onset Alzheimer's disease that interacts with other risk factors, but the nature of such combined effects remains poorly understood. We quantified the impact of APOE-ε4, family history (FH) of dementia, and obesity on white matter (WM) microstructure
The Relationship between Obesity and the High Probability of Dementia Based on the Body Mass Index and Waist Circumference.
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BACKGROUND
For an early detection and prevention of dementia, there are growing concerns about the high-risk group for dementia and mild cognitive impairment. With an increase of obesity and its complications, obesity has become a major public health problem. Therefore, the aim of this study was to
Progressive dementia associated with ataxia or obesity in patients with Tropheryma whipplei encephalitis.
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BACKGROUND
Tropheryma whipplei, the agent of Whipple's disease, causes localised infections in the absence of histological digestive involvement. Our objective is to describe T. whipplei encephalitis.
METHODS
We first diagnosed a patient presenting dementia and obesity whose brain biopsy and
The COVID-19 Effect on the Immune System and Mitochondrial Dynamics in Diabetes, Obesity, and Dementia
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The coronavirus disease 2019 (COVID-19) is a pandemic disease, originated in Wuhan City, China. It is caused by severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) and its biology is still poorly understood. Currently, there are no vaccines and drugs/or agents that can reduce severity of
An introduction to obesity and dementia.
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The increasing prevalence of obesity world-wide has an expected consequent increase in diabetes and cardiovascular disease. Less attention has been paid to the effect of obesity on dementia. This overview discusses methodological issues related to the epidemiologic study of obesity and dementia,
Age at obesity and association with subsequent dementia: record linkage study.
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OBJECTIVE
Obesity in mid-life may increase the risk of subsequent dementia. Our objective was to study this risk, focusing on differences by age at the time of recording of obesity, in a large defined population.
METHODS
A record linkage cohort study was undertaken using national administrative
Examining if being overweight really confers protection against dementia: Sixty-four year follow-up of participants in the Glasgow University alumni cohort study.
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BACKGROUND
Recent large-scale studies suggest that obesity and overweight may confer protection against future dementia. This observation could, however, be generated by reverse causality. That is, weight loss in the incipient phase of dementia ascribed to diminished self-care, including sub-optimal
Neurotoxic chemicals in adipose tissue: A role in puzzling findings on obesity and dementia.
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Midlife obesity is associated with increased risk of dementia, whereas late-life obesity is commonly associated with a lower risk of dementia. Although methodologic issues are often discussed in this apparent risk reversal, chronic exposure to low-dose organochlorine pesticides (OCPs), an emerging
Rising midlife obesity will worsen future prevalence of dementia.
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BACKGROUND
Midlife body weight status has been found to affect late life dementia outcomes. A cohort projections model was developed to assess the impact of midlife body mass index (BMI) profile on dementia in older Australians.
METHODS
A baseline projection using age-sex specific dementia
Midlife obesity and dementia: meta-analysis and adjusted forecast of dementia prevalence in the United States and China.
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OBJECTIVE
Obesity is a risk factor of dementia. Current forecasts of dementia prevalence fail to take the rising obesity prevalence into account.
METHODS
Embase and Medline were searched for observational studies on the association between overweight (BMI 25-30 kg/m(2)) or obesity (BMI > 30 kg/m(2))
Effect of Obesity on Cognitive Impairment in Vascular Dementia Rat Model via BDNF-ERK-CREB Pathway
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The prevalence of vascular dementia continues to increase with no cure. Thus, it is important identify the aggravating factors of vascular dementia to delay disease progression in patients. Obesity is a well-known risk factor for vascular dementia and causes mild cognitive impairment. In the present
Overweight and Obesity in Midlife and Brain Structure and Dementia 26 Years Later: The AGES-Reykjavik Study.
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High adiposity in midlife might increase risk for late-life brain pathology, including dementia. Using data from the prospective Age, Gene/Environment Susceptibility-Reykjavik Study of men and women (born 1907-1935), we studied the associations of overweight and obesity at midlife (mean age, 50
Modest Overweight and Healthy Dietary Habits Reduce Risk of Dementia: A Nationwide Survey in Taiwan.
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BACKGROUND
Evidence of the associations of dietary habits and body mass index with dementia is inconsistent and limited in East Asian countries.
OBJECTIVE
We aim to explore the associations of dietary habits and body mass index with the odds of dementia.
METHODS
Cross-sectional observational
Smoking and Obesity as Risk Factors in Frontotemporal Dementia and Alzheimer's Disease: The HUNT Study.
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