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dementia/protease

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5 resultados

Nanoparticle sensor for measuring protease activity and method for manufacturing the same

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CROSS-REFERENCE TO RELATED APPLICATIONS The present application is a 35 U.S.C. .sctn..sctn.371 national phase conversion of PCT/KR2009/004794, filed Aug. 27, 2009, which claims priority of Korean Patent Application No. 10-2008-0085497, filed Aug. 29, 2008. The PCT International Application was

Secretases related to Alzheimer's dementia

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BACKGROUND OF THE INVENTION 1. Field of the Invention The present invention relates generally to medicine. More specifically, the invention is directed to methods relating to treating or preventing dementia. 2. Background Information Dementia is a neurological disease that results in loss of

Acylaminothiazole derivatives, preparation and therapeutic use thereof

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BACKGROUND OF THE INVENTION Field of the Invention The present invention relates to acylaminothiazole derivatives, their preparation and their therapeutic use. SUMMARY OF THE INVENTION The present invention first provides compounds conforming to the general formula (I): ##STR00002## in which R.sub.1

Compositions and methods for treating beta-amyloid related diseases

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FIELD OF THE TECHNOLOGY The invention generally relates to medicinal chemistry, veterinary medicine and cell biology. In alternative embodiments the invention provides compositions and methods for ameliorating diseases and conditions having a beta-amyloid component, including Alzheimer's disease

Use of acylaminothiazole derivatives as therapeutic agents

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BACKGROUND OF THE INVENTION Field of the Invention The present invention relates to acylaminothiazole derivatives, their preparation and their therapeutic use. SUMMARY OF THE INVENTION The present invention first provides compounds conforming to the general formula (I): ##STR00002## in which R.sub.1
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