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dopa/acidente vascular cerebral
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Brain Correlates of Multimodal Rehabilitation in Chronic Post-stroke Aphasia
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Aphasia is a devastating disorder involving total or partial loss of language. It can affect all communicative, expressive, and receptive modalities, including language production, comprehension, reading, writing, and the ability to gesture. Stroke is the most common cause of aphasia and its
Treadmill in the Rehabilitation of Parkinsonian Gait
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Gait disorders in Parkinson Disease (PD) are due to dopaminergic nigrostriatal pathways degeneration and represent important components of the disability.
In PD, gait is characterized by a significant reduction of stride length. Inadequate flexion at the ankle and knee, reduction of heel strike,
Enhancement of Stroke Rehabilitation With Levodopa
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Trial investigates whether Levodopa/Carbidopa compared to placebo given in addition to standardized rehabilitative therapy in patients with acute ischemic stroke is associated with
1. improvements of physical function based on the patient's self-assessment
2. improvement in patient-self assessed
Subthalamotomy by ExAblate Transcranial System to Treat Motor Features of Parkinson's Disease
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This ExAblate Transcranial system was built atop the ExAblate Body system technology, which has received EMA and CE approvals for the treatment of uterine fibroids and bone metastasis palliation, and is currently being evaluated under various EMA Investigational Device Exemptions "IDE". It should be
Effect of Serotonin and Levodopa in Ischemic Stroke
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Methods. Evaluate 240 consecutive patients with a first ischemic stroke with NIHSS 5-20 without aphasia and with a previous independent functional status (mRS <3). Patients will be randomized into four arms: 1) control group, 2) treatment with citalopram 20 mg / day, 3) group levodopa (sinemet
The Role of Cerebellar Hyperactivity in Parkinson's Disease
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The cerebellum plays an important role in generating well-coordinated locomotion, voluntary limb movements and eye movements (Morton et al. 2004). It is particularly important for balance and limb coordination needed to generate a stable gait pattern (Morton et al. 2006). Specific roles of the
Combining Robotic-Assisted Therapy and Pharmacotherapy in Post-Stroke Rehabilitation
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Every year, approximately 795,000 people suffer a new or recurrent stroke in the United States, meaning that every 40 seconds someone has a stroke. In the United States, stroke is the third most frequent cause of death and the leading cause of lasting hemiparesis and adult disability. Since the
Combinational Rehabilitative Therapy and Functional Brain Imaging for Patients Recovering From Motor Stroke
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The study is designed as a single-blinded randomized controlled trial, preceeded by a Phase 1 pilot trial of the VR physiotherapy and standard therapy only.
Phase 1 will comprise of recruitment of up to 5 patients who have recently suffered a stroke who will be informed that they will receive ten
Phase 2A Study of GM 608 in Mild to Moderate Parkinson Disease
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Background The investigational drug GM608 is a synthetic oligopeptide containing 6 amino acids with a sequence identical to one of the active sites of human Motoneuronotrophic factor (MNTF), also referred to as GM6 in studies. MNTF is a novel human endogenous developmental stage neurotrophin for the
Augmenting Language Therapy for Aphasia: Levodopa
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Stroke is the third leading cause of death and the most common cause of disability in the United States. According to the American Stroke Association, the prevalence of stroke in the U.S. is approximately 4.8 million with approximately 700,000 additional strokes occurring annually. Approximately
Vitamin B6, B12, Folic Acid and Exercise in Parkinson's Disease
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Individuals with Parkinson's disease (PD) have a higher risk of death from coronary artery disease and stroke (Gorell, Johnson, & Rybicki, 1994; Postuma & Lang, 2004). Seventy percent of people with PD suffer from dementia or cognitive impairment. Decreased levels of B vitamins are linked to
Effects of Aerobic Exercise in Parkinson's Disease
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Participants:
The participants were recruited in Spring 2009, 2010, and 2011 through regional newspaper advertisements and solicitations in the Movement Disorders Clinic at the University of Iowa and the Veterans Affairs Medical Center of Iowa City. We phone screened respondents and evaluated
Ranibizumab Therapy for Non-arteritic Ischemic Optic Neuropathy
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Nonarteritic anterior ischemic optic neuropathy (NAION) is the most common acute optic neuropathy in people older than 50 years. It is characterized by sudden partial loss of vision in one eye and has an increased risk of vision loss in the fellow eye. Although cause has not been determined, NAION
Influence of Theta Burst Stimulation and Carbidopa-Levodopa on Motor Performance in Stroke Patients
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OBJECTIVE:
Theta Burst Stimulation (TBS) is a type of sub-threshold repetitive Transcranial Magnetic Stimulation (rTMS) which has effects on the excitability of human motor cortex that outlast stimulation by up to an hour. TBS also affects performance of a motor task for up to 30 minutes after
Potentiation of Procedural Motor Learning in Health and Disease
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Adaptive behavior requires procedural motor learning, i.e. the acquisition of motor skills. Procedural learning is particularly critical in the rehabilitation of chronic motor deficits after stroke. A potent modulator of motor function and learning is found in the endogenous dopaminergic system. The
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