eosinophilic esophagitis/obesidade

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High-fat-diet induced obesity worsens TH2 immune response and immunopathologic characteristics in murine model of Eosinophilic Esophagitis.

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Eosinophilic esophagitis (EoE) is an emergent chronic immune-mediated disease of the esophagus, which affects both children and adults. It is clinically characterized by dysphagia, food impaction and esophageal eosinophilia. Epidemiological studies indicate that obesity can worsen

Obesity and hiatal hernia may be non-allergic risk factors for esophageal eosinophilia in Japanese adults.

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Esophageal eosinophilia (EE) is a basal condition of eosinophilic esophageal disorders including eosinophilic esophagitis (EoE) and asymptomatic EE. EoE is considered as an allergic disorder, while it is unclear whether other non-allergic conditions are involved in the pathophysiology

The complex relationship between eosinophilic esophagitis and gastroesophageal reflux disease.

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That gastroesophageal reflux and eosinophilic esophagitis (EoE) may both lead to esophageal eosinophilia is well known. What is not known is how, if at all, these entities interact to contribute to this pathologic entity in specific patients and how often they occur in patients as synergistic

Esophageal eosinophilia after radiofrequency ablation for Barrett's esophagus.

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Radiofrequency ablation (RFA) with HALO system has been developed as a new treatment option for Barrett's esophagus (BE). It had been observed that some patients had esophageal eosinophilia (EE) infiltration after RFA. The incidence and features of EE after RFA were systematically determined. From a

A Bibliometric Analysis of Clinical and Translational Research in Pediatric Gastroenterology From 1970 to 2017.

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OBJECTIVE Pediatric gastroenterology is a clinical and research discipline principally developed over the past 50 years. Bibliometric methods provide quantitative analysis and identify research trends. Study aims were to characterize the growth and trends in pediatric gastroenterology clinical and

Gastroenterology and hepatology clinical research update: 2005-2006.

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This review highlights areas of clinical research in gastroenterology and hepatology that were published predominantly in the journal Clinical Gastroenterology and Hepatology during the last year and were summarized during the American Gastroenterological Association Presidential Plenary Session in

Upper Gastrointestinal Conditions: Nonmalignant Conditions of the Esophagus.

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Eosinophilic esophagitis (EE) is an allergic disorder of the esophagus. This diagnosis requires the presence of specific symptoms and a significantly elevated number of eosinophils in the esophageal lining as determined by endoscopic biopsies. Symptoms tend to be nonspecific among patients younger

Environmental and lifestyle influences on disorders of the large and small intestine: implications for treatment.

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There is growing evidence that many aspects of our lifestyle and the environment we now live in contribute to the development of disease. The luminal digestive tract is a clear target of the influence of dietary components, alcohol, microbial organisms, and other ingested materials. External factors

[Oesophageal diseases: gastroesophageal reflux disease, Barrett's disease, achalasia and eosinophilic oesophagitis].

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The most important novel findings presented on oesophageal disease in DDW 2015 were the following: 1) GERD: a) hypervigilance seems to be a key pathogenic factor in reflux symptoms refractory to PPI; b) post-reflux swallowing-induced peristaltic waves could be an excellent diagnostic criterion for

Dysphagia: Thinking outside the box.

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Dysphagia is a common symptom that is important to recognise and appropriately manage, given that causes include life threatening oesophageal neoplasia, oropharyngeal dysfunction, the risk of aspiration, as well as chronic disabling gastroesophageal reflux (GORD). The predominant causes of dysphagia

The Esophageal Epithelial Barrier in Health and Disease.

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Dysfunction in the esophageal epithelial barrier function is a major source for morbidity. To better understand the pathophysiologic pathways of the diseases associated with barrier dysfunction, including gastroesophageal reflux disease, eosinophilic esophagitis, Barrett's esophagus, and obesity, it

Presentation and Epidemiology of Gastroesophageal Reflux Disease.

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Gastroesophageal reflux disease (GERD) is the most prevalent gastrointestinal disorder in the United States, and leads to substantial morbidity, though associated mortality is rare. The prevalence of GERD symptoms appeared to increase until 1999. Risk factors for complications of GERD include

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