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epilepsy post-traumatic/hypoxia
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Early post-traumatic seizures in moderate to severe pediatric traumatic brain injury: rates, risk factors, and clinical features.
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We performed a retrospective, observational study at a level I pediatric trauma center of children with moderate-to-severe traumatic brain injury (TBI) from January 2002 to September 2006 to identify clinical and radiographic risk factors for early post-traumatic seizures (EPTS). Two hundred and
Early post-traumatic seizures in children with head injury.
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Post-traumatic seizures (PTS) can be a serious complication of head injury, because they can cause secondary brain damage through increased metabolic requirements, raised intracranial pressure, cerebral hypoxia, and/or excessive release of neurotransmitters. In children, early PTS are more frequent
Fulminant hepatitis after grand mal seizures: mechanisms and role of liver transplantation.
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Fulminant liver failure is a rare complication of grand mal seizures with a high mortality, the prognosis being largely determined by the combination of the hepatic and neurologic insults. The mechanisms of acute liver failure secondary to grand mal epilepsy and the place of liver transplantation in
Prognostic factors and outcome of children with severe head injury: an 8-year experience.
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OBJECTIVE
Our aim was to analyze prognostic factors and their association with outcome among children with severe head injury.
METHODS
We conducted a retrospective study among children with severe head injury admitted to our Pediatric Intensive Care Unit (PICU) from November 1992 to December 2000.
Recurrent postictal pulmonary edema: a case report and review of the literature.
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A 37-year-old woman with a post-traumatic seizure disorder had four well-documented episodes of postictal acute pulmonary edema and respiratory failure. Subtherapeutic blood concentrations of phenytoin were documented on each admission. Each episode followed one or more grand mal seizures and was
Severe head injury in early infancy: analysis of causes and possible predictive factors for outcome.
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OBJECTIVE
The aim of this study was to analyse the causes and prognostic factors for outcome in severe traumatic brain injuries (TBI) in early infancy.
METHODS
We present a retrospective study on 16 infants aged less than 12 months observed over the last 20 years in our department for severe brain
Mammalian target of rapamycin: hitting the bull's-eye for neurological disorders.
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The mammalian target of rapamycin (mTOR) and its associated cell signaling pathways have garnered significant attention for their roles in cell biology and oncology. Interestingly, the explosion of information in this field has linked mTOR to neurological diseases with promising initial studies.
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