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Intractable diarrhea in a boy with vasoactive intestinal peptide-producing ganglioneuroblastoma.

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A 1-year-old boy had intractable diarrhea and symptoms of the watery-diarrhea-hypokalemia-achlorhydria (WDHA) syndrome, a well-known entity in adults. Resection of a ganglioneuroblastoma situated in the neck caused prompt relief of symptoms. The ganglioneuroblastoma in this instance contained the

Intractable diarrhea in children with VIP-secreting ganglioneuroblastomas.

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This paper describes two children with diarrhea, hypokalemia, and VIP-secreting ganglioneuroblastomas, and includes further evidence that VIP is the cause of the loose stools among patients with such tumors. It suggests that the level of this peptide should be measured in pediatric patients with

Rapid changes of serum vasoactive intestinal peptide after removal of ganglioneuroblastoma with watery-diarrhea-hypokalemia-achlorhydria syndrome in a child.

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A 23-month-old girl with intractable diarrhea that had persisted for the past 6 months showed typical evidence of water-diarrhea-hypokalemia-achlorhydria (WDHA) syndrome. Serum vasoactive intestinal peptide (VIP)-like immunoactivity was very high, and urine homovanillic acid and noradrenaline were

[Chronic diarrhea caused by VIP-secreting ganglioneuroblastoma in children. Apropos of a case with a review of the literature].

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A literature review was conducted in relation to a case of chronic diarrhea associated with a VIP (vasoactive intestinal polypeptide) producing ganglioneuroblastoma (GNB), in an 18-month old female baby. This is a rare entity characterized by premonitory, persisting diarrhea, causing fluid and

Multiple-hormone gene expression in ganglioneuroblastoma with watery diarrhea, hypokalemia, and achlorhydria syndrome.

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BACKGROUND It has been reported that vasoactive intestinal peptide (VIP)-producing tumors accompanied by watery diarrhea, hypokalemia, and achlorhydria (WDHA) syndrome often produce multiple hormones biochemically and immunohistochemically. METHODS The authors examined the distribution of several

Ganglioneuroblastoma containing several kinds of neuronal peptides with watery diarrhea syndrome.

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This report presents an adrenal ganglioneuroblastoma containing several kinds of neuronal peptides. The tumour was found in the autopsy case of a 3-year-old girl with clinical manifestation of intractable diarrhea, hypokalemia, achlorhydria, and with elevated levels of plasma vasoactive intestinal

Ataxia and secretory diarrhea: two unusual paraneoplastic syndromes occurring concurrently in the same patient with ganglioneuroblastoma.

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The presence of rare paraneoplastic syndromes, the opsoclonus-myoclonus-ataxia syndrome (OMA), presumably caused by antineuronal antibody production, and diarrhea, caused by vasoactive intestinal peptide (VIP) secreted by neuroblastoma, may strongly signal the presence of neuroblastoma. The authors

[Choleriform diarrhea in a case of ganglioneuroblastoma. Demonstration of a high blood level of vasoactive intestinal peptide (VIP)].

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The case of a 6-month old infant presenting with profuse diarrhea associated with increased plasma V.I.P. (600 pg/ml) is reported. The increased excretion of V.I.P., most probably of tumoral origin may be considered as responsible for the diarrhea. The discovery of an increased plasma level of

Chronic diarrhea in an adult with hypokalemic nephropathy and osteomalacia due to functioning ganglioneuroblastoma.

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Chronic diarrhea in an adult with hypokalemic nephropathy and osteomalacia due to a functioning ganglioneuroblastoma.

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Chronic diarrhea with ganglioneuroblastoma.

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Catecholamines and diarrhea in ganglioneuroblastoma.

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Ganglioneuroblastoma associated with chronic diarrhea and increased excretion of catecholamines: preliminary report.

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[Acute diarrhea as a leading symptom of ganglioneuroblastoma].

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[Ganglioneuroblastoma in a girl with chronic diarrhea and hypokalemia].

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