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hypersensitivity/tyrosine
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Bicyclic heteroaromatic compounds as protein tyrosine kinase inhibitors
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The present invention relates to a series of substituted heteroaromatic compounds, methods for their preparation, pharmaceutical compositions containing them and their use in medicine. In particular, the invention relates to bioisosteres of quinoline and quinazoline derivatives which exhibit protein
Benzo[b]thiophenyl or tetrahydro-benzo[b]thiophenyl modulators of protein tyrosine phosphatases (PTPases)
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FIELD OF THE INVENTION
The present invention relates to novel compounds, to methods for their preparation, to compositions comprising the compounds, to the use of these compounds as medicaments and their use in therapy, where such compounds of Formula 1 are pharmacologically useful inhibitors of
Thiazolyl inhibitors of Tec family tyrosine kinases
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FIELD OF THE INVENTION
The present invention provides for thiazolyl compounds useful as inhibitors of Tec family tyrosine kinases (especially inhibitors of Emt) and to pharmaceutical compositions containing such compounds. The present invention further provides for methods of using such compounds as
Thiazolyl inhibitors of Tec family tyrosine kinases
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FIELD OF THE INVENTION
The present invention provides for thiazolyl compounds useful as inhibitors of Tec family tyrosine kinases (especially inhibitors of Emt) and to pharmaceutical compositions containing such compounds. The present invention further provides for methods of using such compounds as
Thiazolyl inhibitors of Tec family tyrosine kinases
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Entrar Inscrever-se
FIELD OF THE INVENTION
The present invention provides for thiazolyl compounds useful as inhibitors of Tec family tyrosine kinases (especially inhibitors of Emt) and to pharmaceutical compositions containing such compounds. The present invention further provides for methods of using such compounds as
Thiazolyl inhibitors of Tec family tyrosine kinases
Apenas usuários registrados podem traduzir artigos
Entrar Inscrever-se
FIELD OF THE INVENTION
The present invention provides for thiazolyl compounds useful as inhibitors of Tec family tyrosine kinases (especially inhibitors of Emt) and to pharmaceutical compositions containing such compounds. The present invention further provides for methods of using such compounds as
Thiazolyl inhibitors of Tec family tyrosine kinases
Apenas usuários registrados podem traduzir artigos
Entrar Inscrever-se
FIELD OF THE INVENTION
The present invention provides for thiazolyl compounds useful as inhibitors of Tec family tyrosine kinases (especially inhibitors of Emt) and to pharmaceutical compositions containing such compounds. The present invention further provides for methods of using such compounds as
Thiazolyl inhibitors of Tec family tyrosine kinases
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Entrar Inscrever-se
FIELD OF THE INVENTION
The present invention provides for thiazolyl compounds useful as inhibitors of Tec family tyrosine kinases (especially inhibitors of Emt) and to pharmaceutical compositions containing such compounds. The present invention further provides for methods of using such compounds as
2-aminoaryloxazole compounds as tyrosine kinase inhibitors
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The present invention relates to novel compounds selected from 2-aminoaryloxazoles that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative,
2-aminoaryloxazole compounds as tyrosine kinase inhibitors
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The present invention relates to novel compounds selected from 2-aminoaryloxazoles that selectively modulate, regulate, and/or inhibit signal transduction mediated by certain native and/or mutant tyrosine kinases implicated in a variety of human and animal diseases such as cell proliferative,
RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions
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FIELD OF THE INVENTION
The present invention relates to the field of interfering RNA compositions for silencing spleen tyrosine kinase (Syk) and for treatment of a Syk-related inflammatory condition. Such conditions include allergic conjunctivitis, ocular inflammation, dermatitis, rhinitis, asthma,
RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions
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FIELD OF THE INVENTION
The present invention relates to the field of interfering RNA compositions for silencing spleen tyrosine kinase (Syk) and for treatment of a Syk-related inflammatory condition. Such conditions include allergic conjunctivitis, ocular inflammation, dermatitis, rhinitis, asthma,
RNAi-mediated inhibition of spleen tyrosine kinase-related inflammatory conditions
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FIELD OF THE INVENTION
The present invention relates to the field of interfering RNA compositions for silencing spleen tyrosine kinase (Syk) and for treatment of a Syk-related inflammatory condition. Such conditions include allergic conjunctivitis, ocular inflammation, dermatitis, rhinitis, asthma,
Heterocyclic compounds useful as inhibitors of tyrosine kinases
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FIELD OF THE INVENTION
This invention relates to substituted compounds of formula (I): ##STR2##
wherein Ar.sub.1, X, Y, P, Q and Het are defined below, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases resulting from inappropriate cell
Heterocyclic compounds useful as inhibitors of tyrosine kinases
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Entrar Inscrever-se
FIELD OF THE INVENTION
This invention relates to substituted compounds of formula (I): ##STR2##
wherein Ar.sub.1, X, Y, P, Q and Het are defined below, which are useful as inhibitors of certain protein tyrosine kinases and are thus useful for treating diseases resulting from inappropriate cell
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