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insulin resistance/edema
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PPAR ligands that do not cause fluid retention, edema or congestive heart failure
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Entrar Inscrever-se
TECHNICAL FIELD OF THE INVENTION
This invention relates to the field of prevention and treatment of cardiovascular diseases and insulin resistance syndromes. Specifically, this invention relates to compounds that increase both the activity of peroxisome proliferator activated receptors (PPARs) and
PPAR Ligands that do not cause fluid retention, edema or congestive heart failure
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Entrar Inscrever-se
TECHNICAL FIELD OF THE INVENTION
This invention relates to the field of prevention and treatment of cardiovascular diseases and insulin resistance syndromes. Specifically, this invention relates to compounds that increase both the activity of peroxisome proliferator activated receptors (PPARs) and
Medicinal compositions containing diuretic and insulin resistance-improving agent
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BACKGROUND OF THE INVENTION
The present invention relates to new pharmaceutical agents for prophylaxis or treatment of diabetes mellitus comprising an insulin sensitizer and a diuretic, said diuretic having the activity of preventing or treating edema caused by the insulin sensitizer.
It is known
N-benzylindole modulators of PPARG
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BACKGROUND
The peroxisome proliferator active receptors (PPARs), members of the nuclear hormone receptor superfamily, comprise several subtypes, such as PPAR.alpha., PPAR.beta., and PPAR.gamma.. The PPAR.gamma. subtype, also referred to as PPARG, is the target of the glitazone pharmaceutical agents
N-biphenylmethylindole modulators of PPARG
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Entrar Inscrever-se
BACKGROUND
The peroxisome proliferator active receptors (PPARs), members of the nuclear hormone receptor superfamily, comprise several subtypes such as PPAR.alpha., PPAR.beta., and PPAR.gamma.. The PPAR.gamma. subtype, also referred to as PPARG, is the target of the glitazone pharmaceutical agents
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