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Widespread arsenic (As) contamination is a severe environmental and public health concern. Isatis cappadocica, an arsenic hyperaccumulator, holds great potential to clean up As-contaminated soil and groundwater. Iron oxide is one of the most common metal oxides in the natural environment and its
Isatis cappadocica is a well-known arsenic- hyperaccumulator, but there are no reports of its responses to cadmium (Cd). Nitric oxide (NO) is a signaling molecule, which induces cross-stress tolerance and mediates several physio-biochemical processes related to heavy metal toxicity. In this study,

Novel function of N,N-bis(2-chloroethyl)docos-13-enamide for reversal of multidrug resistance in tongue cancer.

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Multidrug resistance (MDR) is a key element in the failure of chemotherapies, and development of agents to overcome MDR is crucial to improving cancer treatments. The overexpression of glutathione-S-transferases (GSTs) is one of the major mechanisms of MDR. Because some agents used in traditional
A hydroponic experiment was conducted to explore the interactive effects of selenium (Se) supplementation (0, 5, and 10 μM) and arsenic (As) toxicity (0, 200, and 400 μM) on the growth, accumulation, and oxidative damage along with defense mechanisms of metallicolous (MP) and non-metallicolous
Arsenic (As) is a toxic metalloid that severely hampers plant growth and also poses health risks for humans through the food chain. Although nitric oxide (NO) is known to improve plant resistance to multiple stresses including metal toxicity, little is known about its role in the As tolerance of
The present study investigated the effects of arsenate and phosphate interaction on growth, lipid peroxidation, arsenic (As) accumulation, phosphorus (P) accumulation, and the activities of some antioxidant enzymes in Isatis cappadocica. Plants were exposed to (50-1200 μmol L-1) arsenate and (5-1600
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