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jimsonweed/antineoplásico

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Preclinical anticancer studies on the ethyl acetate leaf extracts of Datura stramonium and Datura inoxia

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Background: Cancer is a horrific disease relentlessly affecting human population round the globe. Genus Datura encompasses numerous species with reported medicinal uses. However, its potential as a source of natural anticancer agents is

Evaluation of the mutagenic and antimutagenic effects of South African plants.

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Dichloromethane and 90% methanol extracts of 42 South African plants were screened for mutagenicity and antimutagenicity using the Salmonella/microsome mutagenicity assay (Ames) against Salmonella typhimurium TA98 and TA100 bacterial strains in the presence and absence of metabolic activator S9. The

The Biosynthesis Pathway of Swainsonine, a New Anticancer Drug from Three Endophytic Fungi.

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Swainsonine (SW) is the principal toxic ingredient of locoweed plants that causes locoism characterized by a disorder of the nervous system. It has also received widespread attention in the medical field for its beneficial anticancer and antitumor activities. Endophytic fungi, Alternaria sect.

Angiogenesis in the caprine caruncles in non-pregnant and pregnant normal and swainsonine-treated does.

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Microvascular corrosion casts of caruncles from non-pregnant and pregnant doe goats at 4, 7, 10, 13, 16, and 18 weeks were examined with scanning electron microscopy. The internal convex surface of the caruncles of non-pregnant does was covered with capillary meshes of regular diameter and form,
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