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Herbal treatment following post-seizure induction in rat by lithium pilocarpine: Scutellaria lateriflora (Skullcap), Gelsemium sempervirens (Gelsemium) and Datura stramonium (Jimson Weed) may prevent development of spontaneous seizures.

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About 1 week after the induction of status epilepticus in male rats by a single systemic injection of lithium (3 mEq/kg) and pilocarpine (30 g/kg), rats were continuously administered one of three herbal treatments through the water supply for 30 days. A fourth group received colloidal minerals and

Tissue swainsonine clearance in sheep chronically poisoned with locoweed (Oxytropis sericea).

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Locoweed poisoning is seen throughout the world and annually costs the livestock industry millions of dollars. Swainsonine inhibits lysosomal alpha-mannosidase and Golgi mannosidase II. Poisoned animals are lethargic, anorexic, emaciated, and have neurologic signs that range from subtle apprehension

Neurologic disease in range goats associated with Oxytropis sericea (Locoweed) poisoning and water deprivation.

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About 200/2500 Spanish goats foraging on mountain rangelands of western Montana developed neurologic disease with severe rear limb weakness, knuckling of the rear fetlocks, and a hopping gait. Sick goats were of all ages and in good flesh, though they often had dull, shaggy coats. Some mildly

[Datura stramonium poisoning].

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Datura stramonium is a hallucinogenic plant, widely distributed and easily accessible, which contains toxic anticholinergic alkaloids. Voluntary or accidental ingestion can produce serious illness or death. The clinical presentation is similar to that seen in cases of atropine poisoning. Signs and

Teenagers with Jimson weed (Datura stramonium) poisoning.

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We report 2 cases of teenagers who were poisoned with Jimson weed (Datura stramonium) and presented to the emergency department with a severe acute anticholinergic toxidrome after ingestion of several hundred seeds. The patients presented with visual hallucinations, disorientation, incomprehensible

Acute Datura Stramonium poisoning in East of Iran - a case series.

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OBJECTIVE Datura Stramonium (DS) is a common weed along roadsides, in cornfields and pastures and in waste areas. It belongs to the family Solanaceae and its toxic components are tropane belladonna alkaloids. It has been used voluntarily by teenagers for its hallucinogenic effect. The plant is named

Jimsonweed intoxication in adolescents and young adults.

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Seventy-three jimsonweed exposures reported to a regional poison center over a five-year period were reviewed. The ingestors' mean age was 17.3 years (range, 11 to 28 years). The most common route of exposure was oral, and the circumstance was drug abuse or experimentation in the majority of the

[Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center].

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OBJECTIVE To analyze the types, frequency and severity of plant poisonings in Switzerland over 29 years. METHODS Retrospective analysis of severe poisonings with toxic plants reported to the Swiss Toxicological Information Center (STIC). Assessment of the causality, severity of symptoms and the

[Poisoning with Jimson weed. Five cases treated with physostigmine].

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During the autumn of 1995, the National Poisons Information Centre was contacted about several cases of poisoning with Jimson weed (Datura stramonium). Five cases are described here. Upon admission to hospital the patients had moderate to severe anticholinergic symptoms, such as mydriasis, sinus

The dangers of jimson weed and its abuse by teenagers in the Kanawha Valley of West Virginia.

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Jimson weed (Datura stramonium, a member of the Belladonna alkyloid family) is a plant growing naturally in West Virginia and has been used as a home remedy since colonial times. Due to its easy availability and strong anticholinergic properties, teens are using Jimson weed as a drug. Plant parts

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