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β-Alanine supplementation elevates intramuscular carnosine content and attenuates fatigue in men and women similarly but does not change muscle l-histidine content.

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β-Alanine (BA) supplementation results in elevated intramuscular carnosine content, enhancing buffering capacity during intense exercise. Although men have greater muscle carnosine content than women, elevations still appear to occur despite high baseline levels. Recent research has suggested that

Contrasting plasma free amino acid patterns in elite athletes: association with fatigue and infection.

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OBJECTIVE There is little information on the plasma free amino acid patterns of elite athletes against which fatigue and nutrition can be considered. Therefore the aim was to include analysis of this pattern in the medical screening of elite athletes during both especially intense and light training

Changes in urinary amino acids excretion in relationship with muscle activity markers over a professional cycling stage race: in search of fatigue markers.

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The aim of this study was to identify the relationship between metabolic effort, muscular damage/activity indices, and urinary amino acids profile over the course of a strenuous prolonged endurance activity, as a cycling stage race is, in order to identify possible fatigue markers. Nine professional

beta-Alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters.

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Carnosine (beta-alanyl-l-histidine) is present in high concentrations in human skeletal muscle. The ingestion of beta-alanine, the rate-limiting precursor of carnosine, has been shown to elevate the muscle carnosine content. We aimed to investigate, using proton magnetic resonance spectroscopy

[Effects of ß-alanine supplementation on wingate tests in university female footballers].

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BACKGROUND Football is a sport that develops actions intermittent high-intensity exercise using the anaerobic pathway, for that reason, the muscle fatigue would produce primarily by increasing acidosis. Carnosine, which is formed from L-histidine, ß-alanine, has proven to produce an effect "buffer"

Role of beta-alanine supplementation on muscle carnosine and exercise performance.

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In this narrative review, we present and discuss the current knowledge available on carnosine and beta-alanine metabolism as well as the effects of beta-alanine supplementation on exercise performance. Intramuscular acidosis has been attributed to be one of the main causes of fatigue during intense

Beta-alanine supplementation in high-intensity exercise.

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Glycolysis involves the oxidation of two neutral hydroxyl groups on each glycosyl (or glucosyl) unit metabolised, yielding two carboxylic acid groups. During low-intensity exercise these, along with the remainder of the carbon skeleton, are further oxidised to CO(2) and water. But during

[Changes in levels of human nutritious metabolites after exposure to abnormal acceleration of sea state].

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OBJECTIVE To investigate the changes in the levels of human blood nutritious metabolites and its major regulating factors after exposure to abnormal acceleration of sea state, and to provide clues for further investigating the mechanism of fatigue due to maritime operations. METHODS Using randomly

Effect of beta-alanine supplementation on muscle carnosine concentrations and exercise performance.

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High-intensity exercise results in reduced substrate levels and accumulation of metabolites in the skeletal muscle. The accumulation of these metabolites (e.g. ADP, Pi and H(+)) can have deleterious effects on skeletal muscle function and force generation, thus contributing to fatigue. Clearly this

Ergogenic Effects of β-Alanine Supplementation on Different Sports Modalities: Strong Evidence or Only Incipient Findings?

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Brisola, GMP and Zagatto, AM. Ergogenic effects of β-alanine supplementation on different sports modalities: strong evidence or only incipient findings? J Strength Cond Res XX(X): 000-000, 2018-β-Alanine supplementation is a popular nutritional ergogenic aid among the sports community. Due to its

Carnosine treatment for gulf war illness: a randomized controlled trial.

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About 25% of 1990-1991 Persian Gulf War veterans experience disabling fatigue, widespread pain, and cognitive dysfunction termed Gulf War illness (GWI) or Chronic Multisymptom Illness (CMI). A leading theory proposes that wartime exposures initiated prolonged production of reactive oxygen species

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