lichen sclerosus et atrophicus/progesterona

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Topical progesterone as treatment of choice in genital lichen sclerosis et atrophicus in children.

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[Drug treatment in vulvar lichen sclerosus].

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This study was made in the Oncologic Gynecology's surgery of the Department of Obstetrics and Gynecology of the University of Naples. We evaluated the efficacy of local therapy with testosterone and progesterone in Vulvar Lichen Sclerosus. We treated 65 women suffering from Vulvar Lichen Sclerosus.

Lichen sclerosus and squamous hyperplasia of the vulva. A clinical study of medical treatment.

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One hundred thirty-eight cases of nonneoplastic epithelial disorders of the vulva treated with medical therapy from 1984 to 1988 were evaluated at the University of Florence, Florence, Italy. The 67 cases of lichen sclerosus were treated with testosterone propionate or progesterone ointment for 32

Childhood anogenital lichen sclerosus. A case report.

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Childhood lichen sclerosus is a rare disorder. A 4-year-old girl with chronic vulvar pruritus who was initially suspected to be the victim of child abuse was treated. Vulvar biopsy was performed, confirming the diagnosis of lichen sclerosus. The child was treated with 2% progesterone cream, with

Systematic review and meta-analysis of randomized controlled trials on topical interventions for genital lichen sclerosus.

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BACKGROUND Lichen sclerosus (LS) is a chronic inflammatory dermatosis that occurs mainly in the anogenital area and causes itching and soreness. Progressive destructive scarring may result in burying of the clitoris in females and phimosis in males. Affected people have an increased risk of genital

Vulvar lichen sclerosus : pathophysiology and treatment.

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Lichen sclerosus is a chronic disorder of the skin and mucosal surfaces, and is most commonly seen on the female genital skin. It also occurs on other areas of the body. Any age group may be affected, although it is seen more often in elderly women. The exact cause of lichen sclerosus is unknown.

Evidence of androgen receptor expression in lichen sclerosus: an immunohistochemical study.

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OBJECTIVE While topical androgen administration is widely used in the treatment of lichen sclerosus of the vulva, localization and level of expression of androgen receptor (AR) have not been described previously. METHODS Thirty-nine paraffin-embedded punch biopsies of patients with lichen sclerosus

A population-based case-control study of aetiological factors associated with vulval lichen sclerosus.

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We aimed to investigate the association between possible aetiological factors and the risk of developing vulval lichen sclerosus (VLS). A population-based case-control questionnaire study was performed comparing women with a diagnosis of VLS (n= 92), with those attending a general gynaecology clinic

Clinical and histologic effects of topical treatments of vulval lichen sclerosus. A critical evaluation.

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A randomized study was conducted on 79 patients with vulval lichen sclerosus who were treated for three months with four topical drugs including testosterone (2%), progesterone (2%), clobetasol propionate (.05%) and a cream based preparation. To evaluate the efficacy of the treatments, patients were

Topical interventions for genital lichen sclerosus.

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BACKGROUND Lichen sclerosus is a chronic, inflammatory skin condition that most commonly occurs in adult women, although it may also be seen in men and children. It primarily affects the genital area and around the anus, where it causes persistent itching and soreness. Scarring after inflammation

[Cryosurgery--the last resort or a surgical alternative in the treatment of lichen sclerosus et atrophicus of the vulva (LSAV)?].

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BACKGROUND The treatment of LSAV consists mainly of topical corticosteroids, progesterone or testosterone. Often these approaches neither improve the clinical findings nor relieve the symptoms. We evaluated cryotherapy as a possible therapeutic option. METHODS Nine girls (age between 5 and 15 years,

Receptor modifications in vulvar dystrophies before and after treatment with topical hormones: comparison between the dextran-charcoal technique and immunohistochemical evaluation.

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OBJECTIVE The objective of the study was first to quantify estrogen receptors (ERs) and progesterone receptors (PRs) in dystrophic vulvar tissue before and after topical hormone treatment in an attempt to evaluate whether receptor modifications occurred. Second we compared quantitative analysis with

Virilization secondary to topical testosterone.

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Topical testosterone is recognized as a standard treatment for vulvar lichen sclerosus et atrophicus. Systemic androgenic side effects of this medication are widely believed to be uncommon and mild. A case is reported of severe hirsutism with other signs of virilization and markedly elevated serum

Potential adverse effects of prophylactic bilateral salpingo-oophorectomy on skin aging in premenopausal women undergoing hysterectomy for benign conditions.

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OBJECTIVE This study aimed to assess the effects of hysterectomy and bilateral salpingo-oophorectomy (BSO)--compared with the effects of hysterectomy alone--on skin aging in premenopausal women undergoing hysterectomy for benign conditions. METHODS One hundred thirty-five premenopausal women who

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