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7 resultados
Safety of TY027, a Treatment for COVID-19, in Humans
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This is a Phase 1 First-in-Human, Time Lagged, Randomised, Placebo Controlled, Double Blind, Single Ascending Dose Study of TY027 in Healthy Adult Volunteers.
Safety, tolerability and PK of TY027 will be assessed. The dose escalation will include 25 healthy volunteers across four (4) dose cohorts:
-
Safety and Tolerability of an Antibody Against Yellow Fever Virus (TY014) in Humans
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Safety Arm (1A):
Safety Arm is a phase 1A First-in-Human, Time Lagged, Single Ascending Dose Study of TY014 in Healthy Adult Volunteers.
Safety, tolerability and PK of TY014 will be assessed. The dose escalation will include 27 healthy volunteers in five (5) dose cohorts:
- 0.5 mg/kg, N = 2 TY014 +
A Study of Pembrolizumab and Bavituximab in Patients With Advanced Hepatocellular Carcinoma
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This is a non-randomized, open-label, multi-site phase II therapeutic trial of pembrolizumab and bavituximab in patients with locally advanced HCC. Locally advanced or metastatic HCC is defined as disease that is not amenable to surgical and/or locoregional therapies. Subjects must not have received
Antibiotics to Decrease Post ERCP Cholangitis
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OBJECTIVES AND PURPOSE
The aim is to determine whether a brief course of antibiotics following therapeutic ERCP can reduce post-ERCP cholangitis in patients for whom antibiotics are not already indicated.
STUDY DESIGN
The study will be a prospective, randomized trial consisting of 452 patients who
Early EUS in Acute Biliary Pancreatitis
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Biomarker for Wolman Disease (BioWolman)
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Wolman disease (WD) is a rare genetic disorder characterized by complete absence of an enzyme known as lysosomal acid lipase (LIPA). This enzyme is required to breakdown (metabolize) lipids in the body. Without the LIPA enzyme, lipids may abnormally accumulate in the tissues and organs of the body
Laparoscopic Cystogastrostomy Versus Endoscopic Cystogastrostomy
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This study will be conducted in the Department of Surgical Disciplines and Department of Gastroenterology, All India Institute of Medical Sciences, New Delhi. Patients with pancreatic pseudocyst will be randomized to two groups-
Group I- Laparoscopic management of the pseudocyst Group II- Endoscopic
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