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lipase/inflamação
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Lipoprotein lipase and lipoprotein lipase activators in the treatment of inflammatory conditions
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FIELD OF THE INVENTION
The present invention is directed to methods and compositions involving the activation of PPAR.alpha. by either the enzyme lipoprotein lipase (LPL) or by the lipolytic product monoacylglycerol (MAG). It includes topical compositions in which LPL acts on lipophylic substrates
Agent and compositions comprising the same for inhibiting lipases and phospholipases in body fluids, cells and tissues
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1. FIELD OF THE INVENTION
The present invention relates to a protein and composition comprising the protein for inhibiting or reducing lipases and phospholipase enzymes in body fluids, cells, and tissues. The protein as described in the present invention and the composition comprising of the same
Macrophage inflammatory protein 2 (MIP-2)
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RELATED PUBLICATIONS
The Applicants are authors or co-authors of several articles directed to the subject matter of the present invention. These articles supplement those articles listed in U.S. Pat. No. 4,603,106, which earlier articles are incorporated herein by reference. (1) [Applicant Cerami
Macrophage-derived inflammatory mediator (MIP-2)
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RELATED PUBLICATIONS
The Applicants are authors or co-authors of several articles directed to the subject matter of the present invention. These articles supplement those articles listed in U.S. Pat. No. 4,603,106, which earlier articles are incorporated herein by reference. (1) [Applicant Cerami
Composition comprising an antibody to macrophage-derived inflammatory mediator (MIP-2)
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RELATED PUBLICATIONS
The Applicants are authors or co-authors of several articles directed to the subject matter of the present invention. These articles supplement those articles listed in U.S. Pat. No. 4,603,106, which earlier articles are incorporated herein by reference. (1) [Applicant Cerami
Antibody to macrophage-derived inflammatory mediator (MIP-1.alpha. and MIP-1.beta.)
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RELATED PUBLICATIONS
The Applicants are authors or co-authors of several articles directed to the subject matter of the present invention. These articles are in supplementation to those articles listed in U.S. Pat. No. 4,603,106, which earlier articles are incorporated herein by reference. (1)
Macrophage-derived inflammatory mediator (MIP-1.alpha. and MIP-1.beta.)
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RELATED PUBLICATIONS
The Applicants are authors or co-authors of several articles directed to the subject matter of the present invention. These articles are in supplementation to those articles listed in U.S. Pat. No. 4,603,106, which earlier articles are incorporated herein by reference. (1)
Macrophage-derived inflammatory mediator (MIP-1 .alpha. and MIP-1 .beta.)
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RELATED PUBLICATIONS
The Applicants are authors or co-authors of several articles directed to the subject matter of the present invention. These articles are in supplementation to those articles listed in U.S. Pat. No. 4,603,106, which earlier articles are incorporated herein by reference. (1)
Composition comprising antibody to macrophage-derived inflammatory mediator (MIP-.alpha. 1 and MIP-1.beta.)
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RELATED PUBLICATIONS
The Applicants are authors or co-authors of several articles directed to the subject matter of the present invention. These articles are in supplementation to those articles listed in U.S. Pat. No. 4,603,106, which earlier articles are incorporated herein by reference. (1)
Macrophage-derived inflammatory mediator (MIP-1.alpha. and MIP-1.beta.)
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RELATED PUBLICATIONS
The Applicants are authors or co-authors of several articles directed to the subject matter of the present invention. These articles are in supplementation to those articles listed in U.S. Pat. No. 4,603,106, which earlier articles are incorporated herein by reference. (1)
Macrophage-derived inflammatory mediator (MIP-1.alpha. and MIP-1.beta.)
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RELATED PUBLICATIONS
The Applicants are authors or co-authors of several articles directed to the subject matter of the present invention. These articles are in supplementation to those articles listed in U.S. Pat. No. 4,603,106, which earlier articles are incorporated herein by reference. (1)
Macrophage-derived inflammatory mediator (MIP-1.alpha. and MIP-1.beta.)
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RELATED PUBLICATIONS
The Applicants are authors or co-authors of several articles directed to the subject matter of the present invention. These articles are in supplementation to those articles listed in U.S. Pat. No. 4,603,106, which earlier articles are incorporated herein by reference. (1)
Method for measuring the binding sites for macrophage-derived inflammatory mediator (MIP-1.alpha. and MIP-1.beta.)
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RELATED PUBLICATIONS
The Applicants are authors or co-authors of several articles directed to the subject matter of the present invention. These articles are in supplementation to those articles listed in U.S. Pat. No. 4,603,106, which earlier articles are incorporated herein by reference. (1)
Macrophage-derived inflammatory mediator (MIP-1.alpha. and MIP-1.beta.)
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RELATED PUBLICATIONS
The Applicants are authors or co-authors of several articles directed to the subject matter of the present invention. These articles are in supplementation to those articles listed in U.S. Pat. No. 4,603,106, which earlier articles are incorporated herein by reference. (1)
Methods for treating juvenile arthritis with ant-bile salt-stimulated lipase (BSSL) antibodies
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SEQUENCE LISTING
This application incorporates by reference the sequence listing of record in application Ser. No. 13/262,805.
TECHNICAL FIELD OF THE INVENTION
The invention provides methods and pharmaceutical compositions comprising antagonists to the protein Bile Salt-Stimulated Lipase (BSSL) for
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