muscle cramp/hypoxia

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The Effects of Platelet-Activating Factor on Uterine Contractility, Perfusion, Hypoxia, and Pain in Mice.

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It is widely hypothesized that menstrual pain is triggered by prostaglandin synthesis that evokes high-pressure uterine contractions and ischemia. However, the effects of molecules implicated in menstrual pain on uterine contractility, perfusion, and oxygenation in vivo have been rarely

Sensomotor axonal peripheral neuropathy as a first complication of polycythemia rubra vera: A report of 3 cases.

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METHODS Female, 64 FINAL DIAGNOSIS: Polycythemia rubra vera Symptoms: Burning pain • cramps • hypesthesia • itching • paresthesia METHODS - Clinical Procedure: - Specialty: Neurology. OBJECTIVE Unusual clinical course. BACKGROUND The association between polycythemia vera and peripheral neuropathy

[A study of peripheral neural conduction, motor and sensory, in diabetic patients treated with hyperbaric oxygenation].

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BACKGROUND There are some occlusive disorders in the vasa nervorum and metabolic changes disminishing oxygen liberation by erytrocites at the capillary blood vessels, and these disturbances lead to endoneural microhypoxia. Hyperbaric oxygen reverts hypoxia in the diabetic neuropathy. OBJECTIVE We

Travel thrombosis: Pathomechanisms and clinical aspects.

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The possibility of life threatening venous thromboembolism (VTE) associated with long-haul air travel has received increasing attention in recent years. VTE can develop after long travel by car, bus or train, as well. In this paper recent investigational results on the pathomechanism of this special

[Clinical and analytical findings in patients with toxic oil syndrome. Study of a cohort of 758 patients].

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OBJECTIVE To report the symptoms and analytical findings observed in the collective of patients affected with the toxic oil syndrome (TOS) 18 years after the poisoning. METHODS At the Centro de Investigación sobre el Síndrome del Aceite Tóxico (CISAT) we followed the clinical and analytical course

Effect of bicarbonate-containing dialysate on chronic hemodialysis patients: a comparative study.

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Changes in pH and blood gases were studied during hemodialysis with both acetate and bicarbonate dialysates. During acetate dialysis, PaO2 and PaCO2 decreased significantly (P less than 0.05) from 101 +/- 2 to 93 +/- 3 mmHg and from 34.4 +/- 1.0 to 31.8 +/- 0.9 mmHg, respectively, whereas during

Symptoms in hemodialysis patients and their relationship with biochemical and demographic parameters.

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Symptoms can markedly influence the hemodialysis patients well-being and quality of life. The aim of this paper is to study the frequency of symptoms at home and how these relate to biochemical and treatment variables. Seventy-three hemodialysis patients were questioned on the absence, occasional

Phase III trial of paclitaxel plus carboplatin with or without tirapazamine in advanced non-small-cell lung cancer: Southwest Oncology Group Trial S0003.

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OBJECTIVE Tumor hypoxia confers chemotherapy resistance. Tirapazamine is a cytotoxin that selectively targets hypoxic cells. We conducted a phase III clinical trial to determine whether the addition of tirapazamine to paclitaxel and carboplatin offered a survival advantage when used in the treatment

Lactobacillus rhamnosus GG culture supernatant ameliorates acute alcohol-induced intestinal permeability and liver injury.

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Endotoxemia is a contributing cofactor to alcoholic liver disease (ALD), and alcohol-induced increased intestinal permeability is one of the mechanisms of endotoxin absorption. Probiotic bacteria have been shown to promote intestinal epithelial integrity and protect barrier function in inflammatory

Ecological and toxicological effects of inorganic nitrogen pollution in aquatic ecosystems: A global assessment.

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We provide a global assessment, with detailed multi-scale data, of the ecological and toxicological effects generated by inorganic nitrogen pollution in aquatic ecosystems. Our synthesis of the published scientific literature shows three major environmental problems: (1) it can increase the

Activation of HIF-1α and LL-37 by commensal bacteria inhibits Candida albicans colonization.

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Candida albicans colonization is required for invasive disease. Unlike humans, adult mice with mature intact gut microbiota are resistant to C. albicans gastrointestinal (GI) colonization, but the factors that promote C. albicans colonization resistance are unknown. Here we demonstrate that

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