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Role of Montelukast in Modulation of Response to Sepsis in Preterm Infants

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Since inflammatory mediators play a crucial role in the pathophysiology of sepsis so anti-inflammatory treatment, Montelukast, could be a beneficial therapy. The investigators will conduct this pilot, open-labeled, randomized controlled intervention trial on 40 newborns admitted to NICU. The study

Role of Co-trimoxazole in Severe COVID-19 Patients

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Coronavirus disease (COVID-19) caused by SARS-COV2, represents a highly transmissible and potentially fatal disease that is of great global public health concern at this moment. The pandemic situation in Bangladesh is also evolving rapidly with positive cases and deaths increasing each day.

Seasonal Variations and Different Treatment Protocols of Intussusception in Children: Our Centers Experiences

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Intussusception is the invagination of a segment of bowel into an adjacent segment resulting into an intestinal obstruction. It is the most common acquired cause of intestinal obstruction in children aged four months to two years with a peak of incidence between four and nine months of age. Etiology

The Effect of Berberine on Intestinal Function and Inflammatory Mediators in Severe Patients With Covid-19

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Patients aged 18-80 years who confirmed with COVID-19 and classified as severe were enrolled in the study, and then separated randomly into two groups: a berberine group (B group) and a control group (C group). The diagnostic criteria for severe cases are in accordance with the Diagnosis and

Single Shot Lumbar Erector Spinae Plane (ESP) Block in Total Hip Replacement (THR)

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After a pilot study regarding opioid use for patient after THR, the sample size for either treatment or control arm is calculated to be 35 patients per group to achieve adequate power to detect such a difference. Sealed opaque envelopes with allocation inside is prepared forehand and is subsequently

Lidocaine Combined With Low Opioid Anesthesia and Analgesia in Patients With Primary Liver Cancer

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200 patients with primary liver cancer who meet the standard are included. According to the random number, the patients are divided into lidocaine group and conventional analgesia group. Changes in liver and kidney function, blood routine, blood coagulation function and tumor marker

Magnetic Compression Anastomosis for Recanalization of Biliary Stricture

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Biliary anastomotic stricture is a common complication of after end-to-end biliary anastomosis. Magnetic recanalization is a promising way to establish connection of biliary tract after stenosis or completed obstruction. This study is designed to investigate the safety and efficacy of magnetic

Improving Tissue Oxygenation in Breast Reconstruction Surgery

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The purpose of this trial is to evaluate the effects of perioperative hemodynamic therapy (guided by cardiac output monitoring) on tissue oxygenation during (and after) DIEP flap breast reconstruction surgery. We hypothesize that a low-dose, perioperative dobutamine infusion combined with

Prediction of the Efficacy of ctDNA in Immunotherapy for Advanced Gastric Cancer

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Gastric cancer is one of the most common malignant tumors in China, with the second highest incidence and the third highest mortality.Adenocarcinoma accounts for 95% of gastric malignancies and is the most common malignancy of the digestive tract. Seventy percent of the patients with early gastric

Clinical Study of Adipose-derived Stem Cells in the Treatment of Diabetic Foot

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research design: A randomized controlled trial was designed. According to the established inclusion criteria/exclusion criteria, the subjects were randomly divided into two groups by random number table. Each group received Mesenchymal Stem Cells(MSCs)from fat sources and conventional diabetic foot

Oxycodone and Sufentanil for Analgesia in Hip Surgery

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Hip surgery is a common type of orthopedic surgery. The pathologies are complex, including chronic conditions such as femoral head necrosis, primary hip dysplasia, hip joint osteoarthritis and rheumatoid arthritis, as well as acute diseases such as femoral neck fractures and intertrochanteric

Comparison of Pre-op and Post-op Pectoralis Nerve Block

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The current standard of care at the University of Iowa is to receive a pectoralis nerve block (PEC I/II) prior to surgery for mastectomy and reconstruction cases. The investigators will compare whether patients will have better pain control if they were to receive (PEC I/II block) before surgery or

Feasibility of Serratus Plane Block Associated With Sedation in Axillary Dissection

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This study is a prospective case series. All patients should go through a preoperative evaluation with an anesthesiologist. At that time the eligibility for the study will be evaluated and if the patient consent to participate in the study. The following parameters shall be evaluated in the

The Efficacy of Pancreatic Duct Stenting With Rectal Indomethacin in Preventing Post-ERCP Pancreatitis

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Patients with high risk factors for PEP who will be examined and diagnosed by ERCP at 2018.06-2019.12 in the First People's Hospital of Hangzhou are randomly divided into two groups. 2. Record the relevant indicators of each group of patients: 1 before and after surgery 3, 12, 24 h serum amylase

Arnica Montana and Bellis Perennis for Prevention of Seroma After Mastectomy

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Background Seroma is a common surgical complication created by the inflammatory process that follows mastectomy and reconstruction. It is, thus, common practice to insert surgical drains, which often often remain in place for long periods and delay recovery. In light of the many advantages of
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