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olfaction disorders/cancro
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[Hearing disorders, dysosmia and dysgensia in patients undergoing irradiation for head and neck cancer].
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The study included 30 patients who underwent irradiation for head and neck cancer in the Regional Oncology Center. Cobalt 60 was used to irradiate facial--cervical area bilaterally and parotid glands partially. Before and after the irradiation, audiometric test, examination for osmaesthesia and
Anosmin-1 contributes to brain tumor malignancy through integrin signal pathways.
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Anosmin-1, encoded by the KAL1 gene, is an extracellular matrix (ECM)-associated protein which plays essential roles in the establishment of olfactory and GNRH neurons during early brain development. Loss-of-function mutations of KAL1 results in Kallmann syndrome with delayed puberty and anosmia.
Inhibitory effects of superior cervical ganglionectomy on dimethylbenz(a)anthracene-induced mammary tumors in the rat.
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The role of the pineal in regulating the oncogenic processes was explored in Sprague-Dawley female rats by comparing incidence and growth of mammary tumors in animals subjected to superior cervical ganglionectomy (SCGx) or blinding and anosmia (BAs) with that of intact rats treated with
Induction and growth of mammary tumors after superior cervical ganglionectomy in sighted and blinded-anosmic rats.
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Female rats were subjected to superior cervical ganglionectomy (Gx), blinding and anosmia (BAs) or combined procedures (BAsGx). Onset and growth of dimethylbenz(a)anthracene (DBMA)-induced mammary tumors was studied in these animals and compared to tumorigenesis in intact control rats. Carcinostatic
Malignant triton tumour of the sinonasal tract: Case report and literature review.
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BACKGROUND
The objective is to report a rare tumour of the sinonasal tract and conduct a literature review. Malignant triton tumour is a subtype of malignant schwannoma with rhabdomyoblastic differentiation. It is a very rare tumour, with only 15 reported cases involving the sinonasal
Pleomorphic xanthoastrocytoma arising from olfactory groove: a rare location for a rare tumor.
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Pleomorphic xanthoastrocytomas (PXAs) are a rare variety of WHO grade II gliomas in children and young adults. The common site of location of PXAs is temporal or cortical. We present a rare case of PXA presenting as anterior cranial fossa (ACF) base lesion. A 7-year-old male presented with a history
[Anosmia or hyposmia after long-term oral administration of tegafur--improved anosmia].
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Seventeen patients who manifested anosmia or hyposmia after long-oral administration of Tegafur (FT-207) in postoperative chemotherapy for cancer were followed up. Anosmia improved in 9 of 17 patients (52.9%), and the recovery period was between 3 and 42 months after the manifestation, and between 1
Eyebrow supraorbital keyhole craniotomy for olfactory groove meningiomas with endoscope assistance: case series and systematic review of extent of resection, quantification of postoperative frontal lobe injury, anosmia, and recurrence
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Background: Olfactory groove meningiomas (OGMs) are commonly treated with open craniotomy. Endonasal approaches have also been described.
Objective: To present clinical and
Salvage total pelvic exenteration with bilateral v-y advancement flap reconstruction for locally recurrent rectal cancer.
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Total pelvic exenteration for locally recurrent rectal cancer typically requires extensive excision of the pelvic floor with perineal skin. Due to the extensiveness of the procedure and its non-curative nature, it is controversial as purely palliative therapy. A 66-year-old male patient who had
From epistaxis to bone pain-report of two cases illustrating the clinicopathological spectrum of phosphaturic mesenchymal tumour with fibroblast growth factor receptor 1 immunohistochemical and cytogenetic analyses.
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OBJECTIVE
Phosphaturic mesenchymal tumour (PMT) is a rare, recently described neoplastic entity. It is characterized by distinct histological features, which often occur together with oncogenic osteomalacia. Recently, a novel FN1-FGFR1 gene fusion has been described in a subset of PMTs. The aim of
Interstitial pneumonitis in the COVID-19 era: a difficult differential diagnosis in patients with lung cancer
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In this coronavirus 2019 (COVID-19) era, when pneumonitis occurs in patients with lung cancer receiving immune checkpoint inhibitors (ICIs), a major challenge is to make a rapid and correct differential diagnosis among drug-induced pulmonary toxicity, tumour progression, and severe acute respiratory
Acupuncture Therapy in Post-Radiation Head-and-Neck Cancer with Dysgeusia
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Background: Radiation therapy for head-and-neck cancer can cause side-effects, including pain, nausea, vomiting, sensory disorders such as anosmia and dysgeusia, dysphagia, xerostomia, hot flashes, fatigue, sleep disorders, and even anxiety and depression disorders. Therapies using
Pineal gland in rats with 7,12-dimethylbenz(a)anthracene-induced mammary tumors subjected to manipulations known as enhancers of pineal actions.
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The ultrastructure of pinealocytes was studied in rats with 7,12-dimethylbenz(a)anthracene-induced mammary tumors which were subjected to experimental manipulations known as enhancers of pineal actions (anosmia, underfeeding or cold exposure). In these animals we found: (I)--more nuclei with deep
Nutritional Status in Patients with Esophageal Cancer Receiving Chemoradiation and Assessing the Efficacy of Usual Care for Nutritional Managements
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Background: Malnutrition is prevalent in esophageal cancer patients which affects cancer prognosis. The purpose of this study was a comprehensive assessment of nutritional status during Chemoradiation (CRT).
Liposomal treatment of xerostomia, odor, and taste abnormalities in patients with head and neck cancer.
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Smell and taste disorders, sicca symptoms, can be detected in patients with head and neck cancer. The purpose of this study was to assess the utility of local liposomal application in the treatment of patients with head and neck cancers.
Ninety-eight patients with head and neck cancer were included
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