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The patient was a 64-year-old man who felt numbness of the tongue 30 minutes after eating puffer fish (fugu) prepared by an unqualified person. He then felt hotness on the left side of his face and head, followed by left hemi-paresthesia. The patient had obesity and dyslipidemia. On arrival at our
BACKGROUND
The aim of the study was to assess the prevalence of hand paresthesias (HP) and their relationship with pruning activities.
METHODS
A cross-sectional study was conducted among 537 workers pruning grapevines in the region of Champagne. All workers completed a questionnaire about nocturnal
We describe a women of 22 years of age who had had a vertical gastroplasty (as treatment for morbid obesity). She was admitted to hospital with a 4 week history of nausea and vomiting of food. Treatment with intravenous dextrose, without vitamin supplements was started. One week later she complained
OBJECTIVE
To assess topiramate's efficacy and tolerability in a group of obese binge eaters with no neuropsychiatric comorbidity.
METHODS
We consecutively selected 8 obese patients with binge eating disorder (BED) and no medical or psychiatric comorbidity from individuals seeking treatment for
BACKGROUND
Topiramate is an antiepileptic drug known to have effects on weight. In order to use this as a tool to treat eating disorders, it is useful to examine whether these effects can be predicted in certain patients.
OBJECTIVE
To report the effects of topiramate, initiated for the treatment of
OBJECTIVE
Long-term treatment with topiramate reduces body weight and improves insulin sensitivity in obese humans. Our aim was to evaluate the effect of topiramate treatment for 4 weeks on insulin sensitivity and secretion, independent of weight loss.
METHODS
Randomized, double-blind, crossover,
OBJECTIVE
To investigate the efficacy and safety of topiramate in obese subjects with type 2 diabetes treated with metformin.
METHODS
This was a multicenter, double-blind, placebo-controlled trial. All subjects received a non-pharmacological program of diet, exercise and behavioral modification
Obesity is a growing worldwide epidemic that is associated with serious medical complications. Although diet and exercise are often effective treatment in the short run, the weight lost is usually regained unless intensive intervention is maintained. Pharmacological adjunctive measures are clearly
OBJECTIVE
To examine the metabolic effects and body composition changes after topiramate treatment of obese type 2 diabetic patients (DM2) for 11 months.
METHODS
Thirty-eight DM2 on diet or sulfonylurea treatment participated in this randomized double-blind placebo-controlled trial. Thirteen
BACKGROUND
Treatment of obese subjects with topiramate has recently been associated with significant weight loss in a 6-month dose-ranging study.
OBJECTIVE
To investigate the long-term efficacy and safety of topiramate in obese subjects.
METHODS
Randomised, double-blind, placebo-controlled study
OBJECTIVE
To review the use of topiramate for the treatment of binge-eating disorder (BED) associated with obesity.
METHODS
MEDLINE (1966-July 2006) and the Cochrane Database (2006, issue 3) were used to conduct an English-language literature search. Key search terms included eating disorder,
The effect of topiramate on weight and blood pressure (BP) was examined in a randomized, placebo-controlled trial in obese subjects who had hypertension. After a 4-week, placebo, run-in period, 531 obese subjects (body mass index 27 to 50 kg/m(2)) who had established hypertension were randomly
UNASSIGNED
Surgical patients still commonly experience postoperative pain. With the increasing prevalence of obesity, there is a growing demand for surgical procedures by this population. Intraoperative use of methadone has not been well assessed in this population.
UNASSIGNED
Patients with a body
A 56-week randomized controlled trial was conducted to evaluate safety and efficacy of a controlled-release combination of phentermine and topiramate (PHEN/TPM CR) for weight loss (WL) and metabolic improvements. Men and women with class II and III obesity (BMI ≥ 35 kg/m(2)) were randomized to
Carpal tunnel syndrome (CTS) is the most common compressive entrapment neuropathy caused by the compression of the median nerve at the wrist space known as the carpal tunnel. The epidemiologic factors related to CTS include genetic, medical, social, vocational, and demographic factors. The common