Subjects having periapical disease diagnosed clinically and radiographically and free from any other systemic illness. FMD and c-IMT will be determined by ultrasound

Healthy subject. FMD and c-IMT will be determined by ultrasound

Apical Periodontitis

The diameter of the target artery (right brachial artery) will be measured from two- dimensional ultrasound images, with a 70 MHz linear array transducer and a standard 128XP/10 system (Acuson, Mountain View, California, USA).
c-IMT will be assessed by M-mode ultrasonography via a vivid 7 MHz linear array transducer and a standard 128XP/10 system (Acuson, Mountain View, California, USA) with participants in the supine position.

FMD and c-IMT

Post Graduate Institute of Dental Sciences

Association of Endodontic Infection With Cardiovascular Disease.

Association of Endodontic Infection With Cardiovascular Disease Via Non-invasive Assessment of Endothelial Function

The primary outcome variables observed for the study will be the difference in the FMD and c-IMT of the test group and control group.

Postgraduate Institute of Dental Sciences Rohtak

Procedure: SRP Dietary Supplement: Vitamin D3 Oral supplementation 25000 IU once per week for 6 months Other Name: Cholecalciferol

Procedure: SRP Dietary Supplement: Placebo Oral supplementation once per week for 6 months

Generalized Chronic Periodontitis

Vitamin D Deficiency

Oral supplementation 25000 IU once per week for 6 months

Vitamin D3

Oral supplementation once per week for 6 months

Placebo

Cliniques universitaires Saint-Luc

Effects of Vitamin D Supplementation During a Non-surgical Treatment of Generalized Chronic Periodontitis

Effects of Vitamin D Supplementation During a Non-surgical Treatment of Generalized Chronic Periodontitis: A Randomized Double-blinded Placebo Controlled Clinical Trial

It will be decided at the end of the study

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

All patients were scheduled for open flap debridement surgery on at least two quadrants ≥1 weeks apart.One group will receive Low Dose Diclofenac tablets (25mg Diclofeanc and 325 mg paracetamol), BID for 3 days. The patients who are diagnosed with generalized moderate/severe chronic periodontitis will be included in study. For each quadrant, a flap was raised under local anesthesia (2% lignocaine with 1:80,000 epinephrine). In both the quadrants same technique of anesthesia will be employed. The location and the extent of surgery, volume of the local anesthesia given, and time required to perform the surgical procedure will be recorded in the patient file. Patients will be instructed to complete a pain diary chart for 3 days.

Other group will receive Diclofeanc (50mg Diclofenac and 325mg paracetamol), BID for 3 days. The patients who are diagnosed with generalized moderate/severe chronic periodontitis were included in study. For each quadrant, aperiodontal flap was raised under local anesthesia (2% lignocaine with 1:80,000 epinephrine). In both the quadrants same technique of anesthesia will be employed. The location and the extent of surgery, volume of the local anesthesia given, and time required to perform the surgical procedure was recorded in the patient file. Patients were instructed to complete a pain diary chart for 3 days.

Chronic Periodontitis

it is a split mouth design in which one side recieved low dose diclofenac(25mg) after periodontal flap surgery and in next week second side will recieve diclofenac 50mg after flap surgery.

low dose diclofenac

Dental

To Compare Efficacy of Low Dose Diclofenac (25mg) in Management of Postoperative Pain After Periodontal Flap Surgery

To Compare Efficacy of Low Dose Diclofenac (25mg) in Management of Postoperative Pain After Periodontal Flap Surgery: A Clinical Trail.

it messures pain intensity it is an 10cm line anchored by two extremes 0 for no pain and 10 for extreme pain

periodontitis/cefaleia

Association of Endodontic Infection With Cardiovascular Disease.

Effects of Vitamin D Supplementation During a Non-surgical Treatment of Generalized Chronic Periodontitis

To Compare Efficacy of Low Dose Diclofenac (25mg) in Management of Postoperative Pain After Periodontal Flap Surgery

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