Patients will receive Phenylephrine 30 µg/minute by syringe pump infusion for 30 minutes.

Patients will receive Ephedrine 3 mg/ minute by syringe pump infusion for 30 minutes.

Spinal Hypotension

50 patients will receive Phenylephrine 30 µg/minute by syringe pump infusion for 30 minutes.

Phenylephrine

50 patients will receive Ephedrine 3 mg/ minute by syringe pump infusion for 30 minutes.

Ephedrine

Assiut university hospital

Ephedrine and Phenylephrine for Spinal Hypotension

Ephedrine Versus Phenylephrine Infusion for Prevention of Spinal Hypotension During Cesarean Section: Effect on Maternal Cardiodynamics and Fetal Circulation: Randomized Double-blind Study

maternal cardiac output will be done using non-invasive thoracic bio-impedance monitor

uterine blood flow indices will be done using Doppler

Percentage of patients with any complications will be recorded and treated

MOHAMED F. MOSTAFA

Lecturer of Anesthesia and Intensive Care

Assiut University

Subject will receive a phenylephrine infusion to prevent and to treat hypotension associated with spinal anesthesia

Subject will receive an ephedrine infusion to prevent and to treat hypotension associated with spinal anesthesia

Preeclampsia

Hypotension

Ephedrine concentration: 8 mg/mL. The infusion will be initiated immediately after completion of the spinal injection at a rate of 1 mL/min and continued for a minimum of 2 min after which the infusion will be stopped, continued or increased based on the SBP each minute. After each SBP measurement the infusion will be stopped if SBP > 80% baseline, and the infusion will be continued or restarted if the SBP is approximately equal to 80% baseline. The infusion will be increased by 1 mL/min if the SBP < 80% baseline. Each time there is hypotension the patient will receive a 1 mL IV bolus of the study solution and the infusion will be increased by 1 mL/min until delivery.

Phenylephrine concentration: 100 mcg/mL. The infusion will be initiated immediately after completion of the spinal injection at a rate of 1 mL/min and continued for a minimum of 2 min after which the infusion will be stopped, continued or increased based on the SBP each minute. After each SBP measurement the infusion will be stopped if SBP > 80% baseline, and the infusion will be continued or restarted if the SBP is approximately equal to 80% baseline. The infusion will be increased by 1 mL/min if the SBP < 80% baseline. Each time there is hypotension the patient will receive a 1 mL IV bolus of the study solution and the infusion will be increased by 1 mL/min until delivery.

placental insufficiency/vômito

Ephedrine and Phenylephrine for Spinal Hypotension

Phenylephrine in Spinal Anesthesia in Preeclamptic Patients

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