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pteridium aquilinum/antineoplásico
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Bracken-fern extracts induce cell cycle arrest and apoptosis in certain cancer cell lines.
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Bracken fern [Pteridium aquilinem (L.) kuhn (Dennstaedtiaceae)] is one of the most common species on the planet. It has been consumed by humans and animals for centuries. Use by some human groups is because they believe bracken fern is good for health as plant medicine. However, it is also one of
Carcinogenic effects of ptaquiloside in bracken fern and related compounds.
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Consumption of the bracken fern Pteridium aquilinum by cattle has been shown to induce bladder and intestinal carcinomas in cattle and to cause a number of diseases in other farm animals. An unstable glucoside named ptaquiloside, containing a reactive cyclopropane ring, has been isolated from the
Ptaquiloside from bracken (Pteridium spp.) inhibits tumour-infiltrating CD8+ T cells in HPV-16 transgenic mice.
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Bracken is a fern with worldwide distribution. Exposure to bracken toxins such as ptaquiloside is hypothesized to increase the risk of papillomavirus-related cancers of the upper digestive tract. Ptaquiloside is thought to be an immunosupressor, thus allowing for the development of viral lesions. We
Ferns and lycopods--a potential treasury of anticancer agents but also a carcinogenic hazard.
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Many species of seedless vascular plants-ferns and lycopods-have been used as food and folk medicine since ancient times. Some of them have become the focus of intensive research concerning their anticancer properties. Studies on the anticancer effect of crude extracts are being increasingly
Nutrient values and bioactivities of the extracts from three fern species in China: a comparative assessment.
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Pteridium aquilinum, Osmunda cinnamomea Linn, and Athyrium multidentatum (Doll.) Ching are three fern species widely consumed as potherbs and traditional medicinal herbs in China. Nevertheless, no detailed comparative assessments of their nutrient values and bioactivities have been reported. In this
Occurrence and detection of natural mutagens and modifying factors in food products.
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Various food products of plant origin were investigated for the occurrence of natural mutagens using the Salmonella/microsome assay. In general, food plants were freeze-dried and subsequently extracted with a number of solvents. Solvents were evaporated and the residues obtained were tested for
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