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TP53 gene expression, codon 72 polymorphism and human papillomavirus DNA associated with pterygium.
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Pterygium is a disease of unknown origin and pathogenesis that can be vision threatening. Several researchers believe that pterygium is UV-related and that abnormal expression of p53 protein and infection with human papillomavirus (HPV) are risk factors for pterygium, but their experiments have been
Elevation of S100 calcium-binding protein A7 in recurrent pterygium.
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Recurrent pterygium, a common ophthalmic disease, is difficult to treat as its pathogenesis is unclear. To investigate the key genes responsible for the recurrence of pterygium, tissue samples were collected from six patients with primary pterygium (primary group), six patients with recurrent
Characterisation of human tear proteins using high-resolution mass spectrometry.
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BACKGROUND
The proteins found in tears play an important role in maintaining the ocular surface and changes in tear protein components may reflect changes in the health of the ocular surface. Proteomics provides a comprehensive approach for cataloguing all the proteins of the tear proteome, which
Distinct gene subsets in pterygia formation and recurrence: dissecting complex biological phenomenon using genome wide expression data.
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BACKGROUND
Pterygium is a common ocular surface disease characterized by fibrovascular invasion of the cornea and is sight-threatening due to astigmatism, tear film disturbance, or occlusion of the visual axis. However, the mechanisms for formation and post-surgical recurrence of pterygium are not
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