pyridoxine/atrofia

O link é salvo na área de transferência

Escolha o tipo de classificação

Página 1 a partir de 117 resultados

Pyridoxine effects on ornithine ketoacid transaminase activity in fibroblasts from carriers of two forms of gyrate atrophy of the choroid and retina.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

Gyrate atrophy of the choroid and retina that is due to ornithine ketoacid transaminase (OKT) deficiency is an autosomal recessive disorder. Fibroblasts from heterozygotes for the pyridoxine-responsive variant as well as those for the pyridoxine-nonresponsive variant contain intermediate levels of

Pyridoxine-responsive gyrate atrophy of the choroid and retina: clinical and biochemical correlates of the mutation A226V.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

We discovered the missense mutation, A226V, in the ornithine-delta-aminotransferase (OAT) genes of two unrelated patients with gyrate atrophy of the choroid and retina (GA). One patient, who was a compound for A226V and for the premature termination allele R398ter, showed a significant (P < .01)

Pyridoxine neuropathy in rats: specific degeneration of sensory axons.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

When rats received pyridoxine in doses large enough to cause neuropathy in humans, the animals developed gait ataxia that subsided after the toxin was withdrawn. By using quantitative histologic techniques, we found axonal degeneration of sensory system fibers and that the fibers derived from the

Reduction of hyperornithinemia with a low protein, low arginine diet and pyridoxine in patients with a deficiency of ornithine-ketoacid transaminase (OKT) activity and gyrate atrophy of the choroid and retina.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

Five patients with gyrate atrophy of the choroid and retina showed a 60% of greater decline in plasma ornithine levels during a five week trial of a low protein (10--15 g/day), low arginine (0.50--0.75 g/day) diet supplemented with essential amino acids and pyridoxine administration. These declines

Ocular findings in patients with gyrate atrophy on pyridoxine and low-protein, low-arginine diets.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

Five patients, ages 12 to 30, with gyrate atrophy have shown substantial (60% or greater) decreases in plasma ornithine concentrations within four to eight weeks when placed on a therapeutic trial of low-protein (10-15 g/day), low-arginine diets supplemented with essential amino acids (EAA) and

Pyridoxine megavitaminosis produces degeneration of peripheral sensory neurons (sensory neuronopathy) in the dog.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

Pyridoxine, a water-soluble vitamin, produces a sensory neuronopathy when administered in high doses to dogs. Beagles who received a daily oral dose of 300 mg/kg of pyridoxol hydrochloride developed a swaying gait within 9 days. They eventually became unable to walk, but were not weak. Animals were

Genotype-phenotype correlation of a pyridoxine-responsive form of gyrate atrophy.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

Two clinical subtypes of gyrate atrophy (GA) have been defined based on in vivo or in vitro evidence of response to vitamin B6 (pyridoxine), which is the cofactor of the enzyme ornithine aminotransferase (OAT) shown to be defective in GA. We identified the E318K mutation in the OAT gene,

Folic acid, pyridoxine, and cyanocobalamin combination treatment and age-related macular degeneration in women: the Women's Antioxidant and Folic Acid Cardiovascular Study.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

BACKGROUND Observational epidemiologic studies indicate a direct association between homocysteine concentration in the blood and the risk of age-related macular degeneration (AMD), but randomized trial data to examine the effect of therapy to lower homocysteine levels in AMD are lacking. Our

Rapid deterioration in patients with parkinsonism following tryptophan-pyridoxine administration.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

[Contribution to the knowledge of thymic atrophy in the pyridoxine-deficient rat].

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

IMPAIRMENT OF ANTIBODY RESPONSE IN PYRIDOXINE-DEFICIENT RATS.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

Striking impairment of the antibody response to sheep erythrocytes was found in pyridoxine-deficient rats. Deficiencies in the three other B factors required by the rat, and low protein feeding, having effects on body weight comparable to pyridoxine deficiency, failed to influence the antibody

Thiamine, pyridoxine, cyanocobalamin and their combination inhibit thermal, but not mechanical hyperalgesia in rats with primary sensory neuron injury.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

Neuropathic pain after nerve injury is severe and intractable, and current drugs and nondrug therapies offer substantial pain relief to no more than half of affected patients. The present study investigated the analgesic roles of the B vitamins thiamine (B1), pyridoxine (B6) and cyanocobalamin (B12)

Heterogeneity and uniqueness of ornithine aminotransferase mutations found in Japanese gyrate atrophy patients.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

OBJECTIVE To identify mutations in ornithine aminotransferase (OAT) in seven Japanese families with gyrate atrophy (GA), an autosomal recessive chorioretinal degeneration of the eye caused by a generalized biochemical deficiency in OAT; mutations in the OAT gene have shown a high degree of molecular

Molecular pathology of gyrate atrophy of the choroid and retina due to ornithine aminotransferase deficiency.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

Gyrate atrophy (GA) is an autosomal recessive eye disease characterized by progressive loss of vision due to chorioretinal degeneration. It is associated with a deficiency of the mitochondrial enzyme ornithine aminotransferase (OATase) with consequent hyperornithinemia. Although the clinical

Heterogeneity and complementation analysis of fibroblasts from vitamin B6 responsive and non-responsive patients with gyrate atrophy of the choroid and retina.

Apenas usuários registrados podem traduzir artigos

Entrar Inscrever-se

Fibroblasts from four pyridoxine responsive and three non-responsive patients with gyrate atrophy of the choroid and retina have been examined. Responsive patients had higher activity of ornithine ketoacid transaminase (OKT) in cell homogenates and greater incorporation of radioactivity from

Junte-se à nossa
página do facebook

Herbal & Natural Medicine

O mais completo banco de dados de ervas medicinais apoiado pela ciência

Funciona em 55 idiomas
Curas herbais apoiadas pela ciência
Reconhecimento de ervas por imagem
Mapa GPS interativo - marcar ervas no local (em breve)
Leia publicações científicas relacionadas à sua pesquisa
Pesquise ervas medicinais por seus efeitos
Organize seus interesses e mantenha-se atualizado com as notícias de pesquisa, testes clínicos e patentes

Digite um sintoma ou doença e leia sobre ervas que podem ajudar, digite uma erva e veja as doenças e sintomas contra os quais ela é usada.
* Todas as informações são baseadas em pesquisas científicas publicadas