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spinasterol/hymenoxys rusbyi
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Anti-inflammatory action of hydroalcoholic extract, dichloromethane fraction and steroid α-spinasterol from Polygala sabulosa in LPS-induced peritonitis in mice.
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BACKGROUND
Polygala sabulosa A. W. Bennett is a small herb popularly known as "timutu-pinheirinho" that is widely distributed in southern Brazil and that is used to treat disorders of the bowel and kidney and as a topical anesthetic and expectorant in folk medicine. This study was designed to
Identification of the plant steroid α-spinasterol as a novel transient receptor potential vanilloid 1 antagonist with antinociceptive properties.
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The transient receptor potential vanilloid 1 (TRPV1) receptor is relevant to the perception of noxious information and has been studied as a therapeutic target for the development of new analgesics. The goal of this study was to perform in vivo and in vitro screens to identify novel, efficacious,
Chemical constituents and bioactivities of Glinus oppositifolius.
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OBJECTIVE
To isolate the secondary metabolites from the dichloromethane (DCM) extracts of Glinus oppositifolius; to test for the cytotoxicity of a new triterpene, oppositifolone (1); and to test for the hypoglycemic, analgesic, and antimicrobial potentials of 1, DCM and aqueous leaf extracts of G.
[Studies on liposoluble constituents from Momordicae Semen].
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The liposoluble constituents in Momordicae Semen were investigated in the present study. By silica gel, Sephadex LH-20 column chromatography, and semi-preparative HPLC, 22 compounds were isolated and purified from dichloromethane and ethyl acetate fraction. Based on NMR and MS spectra analyses,
Antioxidant activities and triterpenoids isolated from Alternanthera brasiliana (L.) Kuntze leaves.
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The species Alternanthera brasiliana (L.) Kuntze (Amaranthaceae) is a perennial herbaceous plant widely distributed in Brazil's eastern beaches and certain Amazonian regions. Crude ethanolic (70%) extract, fractions (dichloromethane, ethyl acetate and n-butanolic) and the mixture isolated were
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