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thujone/alucinação
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Vincent van Gogh and the thujone connection.
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During his last two years Vincent van Gogh experienced fits with hallucinations that have been attributed to a congenital psychosis. But the artist admitted to episodes of heavy drinking that were amply confirmed by colleagues and there is good evidence to indicate that addiction to absinthe
Monoterpene α-thujone exerts a differential inhibitory action on GABA(A) receptors implicated in phasic and tonic GABAergic inhibition.
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A monoterpene ketone, α-thujone originally attracted attention as a major natural ingredient of absinthe and was suspected to cause adverse effects such as hallucinations and seizures in persons excessively consuming this beverage. Although subsequent studies ruled out any major role of α-thujone in
Thujone--cause of absinthism?
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Habitual abuse of the wormwood spirit absinthe was described in the 19th and 20th centuries as a cause for the mental disorder "absinthism" including the symptoms hallucinations, sleeplessness and convulsions. A controversial discussion is going on if thujone, a characteristic component of the
Absinthe and suicidality.
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Absinthe is an alcoholic drink which is becoming more widely consumed after being banned for many decades. An association between absinthe use and psychiatric symptoms, ranging from impairment of concentration to marked hallucinations and seizures, has been suggested, but evidence remains unclear.
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