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tubocurarine/cárie dentária
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The excitatory action of acetylcholine on intradental sensory units.
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In order to test the hypothesisthat ACh mediates the transmission of pain stimuli from dentin to sensory intradental nerve endings the following experiments were performed. Intradental nerve impulses were recorded by means of low impedance electrodes inserted in dentinal cavities in the tooth of the
The role of movement in the development of a digital flexor tendon.
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D-tubocurarine was injected into the air sac of 8-day chick embryos to prevent movement of the digits of the hind limb. The embryos were paralyzed from the tenth to the eighteenth day, when the experiment was terminated. The immobilization of the flexor digitorum profundus tendons in the tarsus
Intrathoracic pressures in fetal sheep.
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Intrathoracic pressures were investigated in the sheep fetus from 122 to 145 days of gestation. Pressures during fetal apnoea were determined by means of open-ended catheters in the trachea, intrapleural space and amniotic cavity. Measurements made with open water manometers were confirmed by
Synthesis and structure-activity relationships of neuromuscular blocking agents.
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The first use of neuromuscular blocking agents (muscle relaxants) in clinical practice (1942) revolutionised the practice of anaesthesia and started the modern era of surgery. Since 1942 introduction of tubocurarine (18) neuromuscular blocking agents have been used routinely to provide skeletal
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