Treatment of Acute Pharyngo-Tonsillitis With Essential Oils of Aromatic Plants
Cuvinte cheie
Abstract
Descriere
This study compared the efficacy of spray containing aromatic essential oils of Eucalyptus citriodora, Eucalyptus globulus, Mentha piperita, Origanum syriacum, and Rosmarinus Officinalis, against placebo in the treatment of patients with acute viral Pharyngo-tonsillitis.
In- vitro and clinical studies suggest therapeutic potential of aromatic herbs and trees oils in the treatment of Pharyngo-Tonsillitis. The pharmacological and clinical activity of Eucalyptus citriodora, Eucalyptus globulus, Mentha piperita, Origanum syriacum, and Rosmarinus Officinalis, include anti-inflammatory, anti-bacterial and anti-viral activities. Some of these herbs and trees oils have direct activity on the respiratory tract, the coughing reflex and the airflow in the nasal tract.
Datele
| Ultima verificare: | 05/31/2008 |
| Primul depus: | 01/07/2008 |
| Inscriere estimată trimisă: | 02/06/2008 |
| Prima postare: | 02/07/2008 |
| Ultima actualizare trimisă: | 06/12/2008 |
| Ultima actualizare postată: | 06/16/2008 |
| Data actuală de începere a studiului: | 12/31/2007 |
| Data estimată de finalizare primară: | 04/30/2008 |
| Data estimată de finalizare a studiului: | 04/30/2008 |
Stare sau boală
Intervenție / tratament
Dietary Supplement: 1
Dietary Supplement: 2
Fază
Grupuri de brațe
| Braţ | Intervenție / tratament |
|---|---|
| Active Comparator: 1 treatment with spray containing aromatic essential oils of some herbal plants. | Dietary Supplement: 1 3% of mixture containing aromatic essential oils of Eucalyptus citriodora, Eucalyptus globulus, Mentha piperita, Origanum syriacum, and Rosmarinus Officinalis, spraying to the throat. |
| Placebo Comparator: 2 spray containing placebo. | Dietary Supplement: 2 0:1% of Lemon VIP (Florasynth,Israel), spraying to the throat. |
Criterii de eligibilitate
| Vârste eligibile pentru studiu | 18 Years La 18 Years |
| Sexe eligibile pentru studiu | All |
| Acceptă voluntari sănătoși | da |
| Criterii | Inclusion Criteria: - Clinical diagnosis of acute viral pharyngo-tonsillitis. - Active disease less than 48 hours - Patients agree to sign informed consent according to GCP and Israel national regulations. Exclusion Criteria: - Acute follicular tonsillitis. - Peritonsillar abscess. - Under any antibiotically treatment. - Asthma disease. - Under coumadine therapy. - Hyper sensitivity to Aromatic essential oils. - Any immuno-suppressive disease |
Rezultat
Măsuri de rezultate primare
1. To demonstrate a throat pain relief within the first 20 minutes after first administration of treatment with the spray. [20 minutes]
Măsuri de rezultate secundare
1. To demonstrate a reduction of a defined symptoms sum score based on symptoms and signs comparing baseline therapy from the beginning to the end of 3 days treatment. [3 days]
