American Journal of Medicine 1986-Aug
Angioneurotic edema, agranulocytosis, and fatal septicemia following captopril therapy.
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Abstract
Captopril, an angiotensin converting enzyme inhibitor used in the treatment of hypertension, has been associated with hematologic as well as dermatologic side effects. Two patients with captopril-induced angioneurotic edema, one of whom had fatal granulocytopenia and overwhelming polymicrobial sepsis, are presented.