[Kinin system components and blood serum proteinase inhibitors in hemorrhagic fever with renal syndrome].

In polyuric period of hemorrhagic fever with renal syndrome a distinct activation of the kinin system was observed in blood serum of patients; it was manifested as an increase in spontaneous BAEE-esterase and kallikreine activities as well as a decrease in kininogen content. Content of inhibitors of proteinases (alpha 1-antitrypsin) was increased within all the periods of hemorrhagic fever with renal syndrome, beginning from the I preoligouric period. The data obtained suggest that kinins are involved in pathogenesis and clinical manifestations of hemorrhagic fever with the renal syndrome.