[Pulmonary surfactant and its role in the pathogenesis of dust-induced diseases of the respiratory organs in the miners of coal mines].

OBJECTIVE

establishing a relationship between the condition of the pulmonary surfactant and external respiration function in Donbass coal miners with initial and advanced forms of dust-induced lung pathology. One of the early manifestations of lung pathology in miners is increased synthesis and secretion of the surfactant on the alveolar surface with disorders of its functional activity evidencing disorders of lipid excretion from the pulmonary tissue. The presence of albumin in the expired air indicates the presence of alternative processes in the bronchopulmonary apparatus, and highest albumin content in patients with pneumoconiosis and chronic dust-induced bronchitis may be an index of activity of the inflammatory process.